Tag Archives: SHARE

Discrete choice modeling for the quantification of health states: the case of the EQ-5D






Objectives: Probabilistic models have been developed to establish the relative merit of subjective phenomena by means of specific judgmental tasks involving discrete choices (DCs). The attractiveness of these DC models is that they are embedded in a s… Continue reading

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Potential processes involved in the initiation and maintenance of whiplash-associated disorders: discussion paper 3






STUDY DESIGN: Nonsystematic review and discussion of the etiological processes involved in whiplash-associated disorders (WAD). OBJECTIVE: To summarize the research and identify priorities for future research. SUMMARY OF BACKGROUND DATA: Although ther… Continue reading






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Preventing weight gain by lifestyle intervention in a general practice setting – three-year results of a randomized controlled trial






Background: Weight regain after initial loss of weight is common, which indicates a need for lifestyle counseling aimed at preventing weight gain instead of weight loss. This study was conducted to determine whether structured lifestyle counseling by … Continue reading






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Changes in lifestyle habits after counselling by nurse practitioners: 1-year results of the Groningen Overweight and Lifestyle study






Objectives: The Groningen Overweight and Lifestyle (GOAL) study primarily aims at preventing weight gain by nurse practitioners (NP) guided by a standardized computerized software program. Since favourable changes in physical activity (PA) and diet ma… Continue reading






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Nonpharmacologic treatments for childhood constipation: systematic review






OBJECTIVE: To summarize the evidence and assess the reported quality of studies concerning nonpharmacologic treatments for childhood constipation, including fiber, fluid, physical movement, prebiotics, probiotics, behavioral therapy, multidisciplinary… Continue reading






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Long-term effects of alcohol policies: An economic perspective






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Patients with more severe symptoms benefit the most from an intensive multimodal programme in patients with fibromyalgia






PURPOSE: Patients with fibromyalgia (FM) experience symptoms over a long period of time impacting their quality of life (QoL). Patients are often treated in multimodal programmes that combine physical and cognitive treatment modalities. Purpose of thi… Continue reading






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Factors associated with functional capacity test results in patients with non-specific chronic low back pain: A systematic review






Introduction: Functional capacity tests are standardized instruments to evaluate patients’ capacities to execute work-related activities. Functional capacity test results are associated with biopsychosocial factors, making it unclear what is being mea… Continue reading






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The evolving role of the pharmacist – how can pharmacists drive medication error prevention?






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Participation as an outcome measure in psychosocial oncology: content of cancer-specific health-related quality of life instruments






PURPOSE: To examine to what extent the concept and the domains of participation as defined in the International Classification of Functioning, Disability and Health (ICF) are represented in general cancer-specific health-related quality of life (HRQOL… Continue reading






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In vitro evaluation of the iValve: a novel hands-free speech valve






OBJECTIVES:
We performed in vitro evaluation of a novel, disposable, automatic hands-free tracheostoma speech valve for laryngectomy patients based upon the principle of inhalation. The commercially available automatic speech valves close upon strong… Continue reading






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The course of untreated anxiety and depression, and determinants of poor one-year outcome: a one-year cohort study






Background: Little is known about the course and outcome of untreated anxiety and depression in patients with and without a self-perceived need for care. The aim of the present study was to examine the one-year course of untreated anxiety and depressi… Continue reading






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Economic evaluation and the postponement of health care costs






The inclusion of medical costs in life years gained in economic evaluations of health care technologies has long been controversial. Arguments in favour of the inclusion of such costs are gaining support, which shifts the question from whether to how to include these costs. This paper elaborates on the issue how to include cost in life years gained in cost effectiveness analysis given the current practice of economic evaluations in which costs of related diseases are included. We combine insights from the theoretical literature on the inclusion of unrelated medical costs in life years gained with insights from the so-called ‘red herring’ literature. It is argued that for most interventions it would be incorrect to simply add all medical costs in life years gained to an ICER, even when these are corrected for postponement of the expensive last year of life. This is the case since some of the postponement mechanism is already captured in the unadjusted ICER by modelling the costs of related diseases. Using the example of smoking cessation, we illustrate the differences and similarities between different approaches. The paper concludes with a discussion about the proper way to account for medical costs in life years gained in economic evaluations. Copyright (C) 2010 John Wiley & Sons, Ltd Continue reading






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Pneumococcal conjugate vaccination and nasopharyngeal acquisition of pneumococcal serotype 19A strains






Context The rapid increase in multiresistant serotype 19A as a cause of invasive and respiratory pneumococcal disease has been associated in time with the widespread implementation of 7-valent pneumococcal conjugate vaccination (PCV-7) in several coun… Continue reading






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The TOPSHOCK study: Effectiveness of radial shockwave therapy compared to focused shockwave therapy for treating patellar tendinopath – design of a randomised controlled trial






Background: Patellar tendinopathy is a chronic overuse injury of the patellar tendon that is especially prevalent in people who are involved in jumping activities. Extracorporeal Shockwave Therapy is a relatively new treatment modality for tendinopath… Continue reading






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Impact of the HYPITAT trial on doctors’ behaviour and prevalence of eclampsia in the Netherlands






Please cite this paper as: van der Tuuk K, Koopmans C, Groen H, Mol B, van Pampus M for the HYPITAT study group. Impact of the HYPITAT trial on doctors’ behaviour and prevalence of eclampsia in the Netherlands. BJOG 2011; DOI: 10.1111/j.1471-0528.2011.03138.x. We questioned if participation in the HYPITAT trial (induction of labour versus expectant monitoring in women with gestational hypertension or pre-eclampsia at term) impacted implementation of its results and subsequently maternal health. We identified women with hypertensive disease from the Perinatal Registry, and distinguished the period before, during and after the trial. We included 43 641 women. Induction of labour increased from 58.3 to 67.1% (P Continue reading






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Glycaemic control and the risk of mortality in elderly type 2 diabetic patients (ZODIAC-20)






P>Aims: Studies on macrovascular consequences of glucose control in elderly patients (> 75 years) with type 2 diabetes mellitus (T2DM) are lacking. The present study aimed to investigate the relationship between HbA(1c) and mortality in this specific population. Methods: Between 1998 and 1999, 374 primary care patients with T2DM aged older than 75 years participated in the Zwolle Outpatient Diabetes project Integrating Available Care study, a prospective observational study. Early 2009, data on mortality were collected. Updated means for annually measured HbA(1c) values were calculated after a follow-up time of 10 years. Updated mean HbA(1c) was used as a time-dependent covariate in a Cox proportional hazard model. Main outcome measures were all-cause and cardiovascular disease (CVD) mortality. Analyses were performed in strata according to diabetes duration (= 11 years). Results: In the group with a diabetes duration = 5 years. Conclusion: Poor glycaemic control is related to increased all-cause and CVD mortality in patients > 75 years with T2DM of short duration ( Continue reading






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Lower blood pressure associated with higher mortality in elderly diabetic patients (ZODIAC-12)






Objective: to investigate the relationship between blood pressure over time and mortality in elderly patients with type 2 diabetes mellitus (T2DM). Design: prospective observational cohort stud). Setting: primary care, Zwolle, The Netherlands. Subjects: patients with T2DM aged 60 years and older (n = 881). The cohort was divided into two age categories: 60-75 years and older than 75 years. Methods: updated means for systolic, diastolic and pulse pressures were calculated after a median follow-up time of 9.8 years. These values were used as time-dependent covariates in a Cox proportional hazard model. Main outcome measures were all-cause and cardiovascular mortality. Results: all of the blood pressure measures were inversely related to all-cause mortality in elderly diabetic patients (>75 years). Furthermore, these relationships were specifically found in elderly patients treated with antihypertensive medication at baseline. A decrease of 10 mm Hg in systolic blood pressure, diastolic blood pressure and pulse pressure led to a mortality increase of 20% [95% confidence interval (95% CI): 12-27%], 26% [95% CI: 12%-38%] and 20% [95% CI: 10%-29%], respectively. In the low age group (60-75 years), no relationship was found between blood pressure and mortality. Conclusions: blood pressure is a marker for mortality in elderly T2DM patients; however, the relationship is inverse Continue reading






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If you try to stop smoking, should we pay for it? The cost-utility of reimbursing smoking cessation support in the Netherlands






Background Smoking cessation can be encouraged by reimbursing the costs of smoking cessation support (SCS). The short-term efficiency of reimbursement has been evaluated previously. However, a thorough estimate of the long-term cost-utility is lacking… Continue reading






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AKT1 Moderation of Cannabis-Induced Cognitive Alterations in Psychotic Disorder






Genetic variation in AKT1 may be associated with sensitivity to the psychotomimetic effects of cannabis as well as with increased risk for psychotic disorder following cannabis use. Investigation of the effect of this interaction on relevant intermedi… Continue reading






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