Tag Archives: PubMed

Dysfunctional attitudes or extreme response style as predictors of depressive relapse and recurrence after mobile cognitive therapy for recurrent depression.

Dysfunctional attitudes or extreme response style as predictors of depressive relapse and recurrence after mobile cognitive therapy for recurrent depression.
J Affect Disord. 2018 Sep 08;243:48-54
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[Factors influencing the referral of nursing home patients to the hospital].

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[Factors influencing the referral of nursing home patients to the hospital].
Tijdschr Gerontol Geriatr. 2018 Sep 10;:
Authors: Huls M, Pouw MA, Nieuwenhuizen N, van Munster BC, de Rooij SE
A… Continue reading

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Cancer Survivorship and Palliative Care: Shared Progress, Challenges, and Opportunities.

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Cancer Survivorship and Palliative Care: Shared Progress, Challenges, and Opportunities.
Cancer. 2018 Sep 11;:
Authors: Geerse OP, Lakin JR, Berendsen AJ, Alfano CM, Nekhlyudov L
PMID: 30204… Continue reading

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Mother’s knowledge on prevention of mother-to-child transmission of HIV, Ethiopia: A cross sectional study.

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Mother’s knowledge on prevention of mother-to-child transmission of HIV, Ethiopia: A cross sectional study.
PLoS One. 2018;13(9):e0203043
Authors: Alemu YM, Habtewold TD, Alemu SM
Abstract
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A case report of a young adult with progressive bloody diarrhea, protein losing enteropathy and extended polyposis coli.

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A case report of a young adult with progressive bloody diarrhea, protein losing enteropathy and extended polyposis coli.
Gastroenterology. 2018 Sep 08;:
Authors: Borgerink MMH, Weersma RK, Visschedi… Continue reading

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Antipsychotic treatments: who is really failing here? – Authors’ reply.

Antipsychotic treatments: who is really failing here? – Authors’ reply.
Lancet Psychiatry. 2018 Sep 05;:
Authors: Kahn RS, Sommer IE
PMID: 30196054 [PubMed – as supplied by publisher]
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Viability criteria for functional assessment of donor livers during normothermic machine perfusion.

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Viability criteria for functional assessment of donor livers during normothermic machine perfusion.
Liver Transpl. 2018 Sep 07;:
Authors: van Leeuwen OB, de Meijer VE, Porte RJ
Abstract
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Effects of prophylactic antibiotics on patients with stable COPD: a systematic review and meta-analysis of randomized controlled trials.

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Effects of prophylactic antibiotics on patients with stable COPD: a systematic review and meta-analysis of randomized controlled trials.
J Antimicrob Chemother. 2018 Sep 04;:
Authors: Wang Y, Zijp … Continue reading

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Use of gentamicin-impregnated beads or sponges in the treatment of early acute periprosthetic joint infection: a propensity score analysis.

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Use of gentamicin-impregnated beads or sponges in the treatment of early acute periprosthetic joint infection: a propensity score analysis.
J Antimicrob Chemother. 2018 Sep 05;:
Authors: Wouthuyzen… Continue reading

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The influence of eukaryotic chromatin state on CRISPR-Cas9 editing efficiencies.

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The influence of eukaryotic chromatin state on CRISPR-Cas9 editing efficiencies.
Curr Opin Biotechnol. 2018 Sep 03;55:68-73
Authors: Verkuijl SA, Rots MG
Abstract
CRISPR/Cas technol… Continue reading

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Comparing Cementing Techniques in Total Knee Arthroplasty: An In Vitro Study.

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Comparing Cementing Techniques in Total Knee Arthroplasty: An In Vitro Study.
J Knee Surg. 2018 Sep 06;:
Authors: Wetzels T, van Erp J, Brouwer RW, Bulstra SK, van Raay JJAM
Abstract
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An above-knee compression garment does not improve passive knee joint position sense in healthy adults.

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An above-knee compression garment does not improve passive knee joint position sense in healthy adults.
PLoS One. 2018;13(9):e0203288
Authors: Négyesi J, Mobark A, Zhang LY, Hortobagyi T, Nagatomi R… Continue reading

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Prenatal exposure to persistent organic pollutants and cognition and motor performance in adolescence.

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Prenatal exposure to persistent organic pollutants and cognition and motor performance in adolescence.

Environ Int. 2018 Aug 29;121(Pt 1):13-22

Authors: Berghuis SA, Van Braeckel KNJA, Sauer PJJ, Bos AF

Abstract
BACKGROUND: Prenatal exposure to persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs), was found to be associated with poorer neurological development in children. Knowledge about the effects on outcomes until adolescence is limited.
OBJECTIVES: To determine whether prenatal exposure to POPs, particularly hydroxylated PCBs (OH-PCBs), is associated with cognitive and motor development in 13- to 15-year-old children.
METHODS: This prospective observational cohort study is part of the Development at Adolescence and Chemical Exposure (DACE)-study, a follow-up of two Dutch birth cohorts. Maternal pregnancy serum levels of PCB-153 and three OH-PCBs were measured, in part of the cohort also nine other PCBs and three OH-PCBs, and in another part five polybrominated diphenyl ethers (PBDEs), dichloroethene (DDE), pentachlorophenol (PCP) and hexabroomcyclododecane (HBCDD). Of the 188 invited adolescents, 101 (53.7%) participated, 55 were boys. Cognition (intelligence, attention, verbal memory) and motor performance (fine motor, ball skills, balance) were assessed. Scores were classified into ‘normal’ (IQ > 85; scores > P15) and ‘(sub)clinical’ (IQ ≤ 85; scores ≤ P15). We used linear and logistic regression analyses, and adjusted for maternal education, maternal smoking, maternal alcohol use, breast feeding, and age at examination.
RESULTS: Several OH-PCBs were associated with more optimal sustained attention and balance. PCB-183 was associated with lower total intelligence (OR: 1.29; 95%CI:0.99-1.68; P = .060), and HBCDD with lower performance intelligence (OR: 3.62; 95%CI:0.97-13.49; P = .056). PCBs, OH-PCBs and PBDEs were negatively associated with verbal memory.
CONCLUSIONS: Prenatal background exposure to several POPs can influence neuropsychological outcomes in 13- to 15-year-old Dutch adolescents, although exposure to most compounds does not have clinically relevant consequences at adolescence.

PMID: 30172231 [PubMed – as supplied by publisher]

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High-resolution analysis of the pneumococcal transcriptome under a wide range of infection-relevant conditions.

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High-resolution analysis of the pneumococcal transcriptome under a wide range of infection-relevant conditions.
Nucleic Acids Res. 2018 Aug 27;:
Authors: Aprianto R, Slager J, Holsappel S, Veening JW
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Catalytic regio- and enantioselective alkylation of conjugated dienyl amides.

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Catalytic regio- and enantioselective alkylation of conjugated dienyl amides.
Angew Chem Int Ed Engl. 2018 Aug 24;:
Authors: Harutyunyan SR, Guo Y, Kootstra J
Abstract
We have develop… Continue reading

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Psychological morbidity and general health among family caregivers during end-of-life cancer care: A retrospective census survey.

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Psychological morbidity and general health among family caregivers during end-of-life cancer care: A retrospective census survey.

Palliat Med. 2018 Aug 21;:269216318793286

Authors: Grande G, Rowland C, van den Berg B, Hanratty B

Abstract
BACKGROUND: Family carers provide vital support for patients towards end-of-life, but caregiving has considerable impact on carers’ own health. The scale of this problem is unknown, as previous research has involved unrepresentative samples or failed to fully capture caregiving close to death.
AIM: To quantify level of psychological morbidity and general health among a census sample of carers of people with cancer at end-of-life, compared to population reference data.
DESIGN: National 4-month post-bereavement postal census survey of family carers of people who died from cancer, retrospectively measuring carers’ psychological health (General Health Questionnaire-12) and general health (EuroQoL EQ-Visual Analogue Scale) during the patient’s last 3 months of life.
PARTICIPANTS: N = 1504 (28.5%) of all 5271 people who registered the death of a relative from cancer in England during 2 weeks in 2015 compared with data from the Health Survey for England 2014 ( N = 6477-6790).
RESULTS: Psychological morbidity at clinically significant levels (General Health Questionnaire-12 ⩾4) was substantially higher among carers than the general population (83% vs 15%), with prevalence five to seven times higher across all age groups. Overall, carers’ general health scores were lower than population scores, median 75 (interquartile range, 50-80) versus 80 (interquartile range, 70-90), but differences were more marked at younger ages. Female carers had worse psychological morbidity and general health than male carers.
CONCLUSION: Levels of psychological morbidity among family carers during end-of-life caregiving are far higher than indicated by previous research, indicating a substantial public health problem. Consistent assessment and support for carers to prevent breakdown in caregiving may produce cost savings in long term.

PMID: 30130458 [PubMed – as supplied by publisher]

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New European privacy regulation: Assessing the impact for digital medicine innovations.

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New European privacy regulation: Assessing the impact for digital medicine innovations.
Eur Psychiatry. 2018 Aug 16;54:57-58
Authors: Mulder T, Jagesar RR, Klingenberg AM, P Mifsud Bonnici J, Kas MJ
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Authors’ Response to Braillon’s Comment on: “Limited Evidence for Risk Factors for Proarrhythmia and Sudden Cardiac Death in Patients Using Antidepressants: Dutch Consensus on ECG Monitoring”.

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Authors’ Response to Braillon’s Comment on: “Limited Evidence for Risk Factors for Proarrhythmia and Sudden Cardiac Death in Patients Using Antidepressants: Dutch Consensus on ECG Monitoring”.

Drug Saf. 2018 Aug 17;:

Authors: Simoons M, Seldenrijk A, Mulder H, van Roon E, Bakker R, Ruhé H

PMID: 30120740 [PubMed – as supplied by publisher]

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A design for external quality assessment for the analysis of thiopurine drugs: pitfalls and opportunities.

A design for external quality assessment for the analysis of thiopurine drugs: pitfalls and opportunities.
Clin Chem Lab Med. 2018 Aug 15;:
Authors: Robijns K, van Luin M, Jansen RTP, Neef C, Touw DJ
PMID: 30… Continue reading

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The efficacy of computerized cognitive drill and practice training for patients with a schizophrenia-spectrum disorder: A meta-analysis.

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The efficacy of computerized cognitive drill and practice training for patients with a schizophrenia-spectrum disorder: A meta-analysis.

Schizophr Res. 2018 Aug 07;:

Authors: Prikken M, Konings MJ, Lei WU, Begemann MJH, Sommer IEC

Abstract
BACKGROUND: Computerized methods for improving cognitive functioning in schizophrenia have gained popularity during the past decades. Therefore, this study evaluates the available evidence for the efficacy of computerized cognitive drill and practice training for patients with schizophrenia-spectrum disorders.
METHODS: A systematic search was carried out using PubMed, Embase, Cochrane Database of Systematic Reviews, and PsycINFO. A meta-analysis was performed to compare cognitive drill and practice training in patients with a schizophrenia-spectrum disorder with non-cognitively oriented control conditions. The primary outcome was cognitive functioning. Secondary outcome measures included psychotic symptoms, depressive symptoms, and functional outcomes. Effect sizes (ES) for all included studies were calculated as Hedges’ g.
RESULTS: 24 studies were included with 1262 patients in total. Compared to a control condition, patients receiving computerized cognitive drill and practice training showed significantly more improvement on attention (ES = 0.31, p = 0.001), working memory (ES = 0.38, p < 0.001), positive symptoms (ES = 0.31, p = 0.003), and depressive symptoms (ES = 0.37, p = 0.002). Small, marginally significant effect sizes were found for processing speed, verbal and visual learning and memory, and verbal fluency. However, significant effects on functional outcomes and social cognition were absent.
DISCUSSION: The current study showed evidence for the efficacy of computerized cognitive drill and practice training in patients with schizophrenia-spectrum disorders. However, the absence of effects on social cognition and functional outcomes questions the generalization of treatment effects. Together, these results stimulate further development of computerized training programs for schizophrenia that not only improve cognitive functioning, but also generalize cognitive improvement to functional outcomes.

PMID: 30097278 [PubMed – as supplied by publisher]

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