Distinctive Responses in an In Vitro Human Dendritic Cell-Based System upon Stimulation with Different Influenza Vaccine Formulations

Distinctive Responses in an In Vitro Human Dendritic Cell-Based System upon Stimulation with Different Influenza Vaccine Formulations

Tapia-Calle, G., Stoel, M., de Vries-Idema, J. & Huckriede, A. 9-Aug-2017 In : Vaccines. 5, 3, 17 p., 12

Research output: Scientific – peer-reviewArticle

Original language English
Article number 12
Number of pages 17
Journal Vaccines
Volume 5
Issue number 3
State Published – 9-Aug-2017
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Allergen immunotherapy for allergic rhinoconjunctivitis: a systematic overview of systematic reviews

Allergen immunotherapy for allergic rhinoconjunctivitis: a systematic overview of systematic reviews

Nurmatov, U., Dhami, S., Arasi, S., Roberts, G., Pfaar, O., Muraro, A., Ansotegui, I. J., Calderon, M., Cingi, C., Durham, S., van Wijk, R. G., Halken, S., Hamelmann, E., Hellings, P., Jacobsen, L., Knol, E., Larenas-Linnemann, D., Lin, S. Y., Maggina, V., Oude-Elberink, H., Pajno, G., Panwankar, R., Pastorello, E., Pitsios, C., Rotiroti, G., Timmermans, F., Tsilochristou, O., Varga, E-M., Wilkinson, J., Williams, A., Worm, M., Zhang, L. & Sheikh, A. 8-Aug-2017 In : Clinical and translational allergy. 7, 16 p., 24

Research output: Scientific – peer-reviewReview article

Original language English
Article number 24
Number of pages 16
Journal Clinical and translational allergy
Volume 7
State Published – 8-Aug-2017
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The oxygen reserve index (ORI): a new tool to monitor oxygen therapy

The oxygen reserve index (ORI): a new tool to monitor oxygen therapy

Scheeren, T. W. L., Belda, F. J. & Perel, A. 8-Aug-2017 In : Journal of clinical monitoring and computing.

Research output: Scientific – peer-reviewReview article

Original language English
Journal Journal of clinical monitoring and computing
State E-pub ahead of print – 8-Aug-2017
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Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies

Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies

Abagnale, G., Sechi, A., Steger, M., Zhou, Q., Kuo, C-C., Aydin, G., Schalla, C., Müller-Newen, G., Zenke, M., Costa, I. G., van Rijn, P., Gillner, A. & Wagner, W. 8-Aug-2017 In : Stem Cell Reports. 9, 2, p. 654-666 13 p.

Research output: Scientific – peer-reviewArticle

Original language English
Pages (from-to) 654-666
Number of pages 13
Journal Stem Cell Reports
Volume 9
Issue number 2
State Published – 8-Aug-2017
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Inflammatory Bowel Diseases: Review of Known Environmental Protective and Risk Factors Involved.

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Inflammatory Bowel Diseases: Review of Known Environmental Protective and Risk Factors Involved.

Inflamm Bowel Dis. 2017 Aug 02;:

Authors: van der Sloot KWJ, Amini M, Peters V, Dijkstra G, Alizadeh BZ

Abstract
Inflammatory bowel diseases consisting of Crohn’s disease and ulcerative colitis are chronic inflammatory diseases of the gastrointestinal tract. In addition to genetic susceptibility and disturbances of the microbiome, environmental exposures forming the exposome play an important role. Starting at birth, the cumulative effect of different environmental exposures combined with a predetermined genetic susceptibility is thought to cause inflammatory bowel disease. All these environmental factors are part of a Western lifestyle, suiting the high incidence rates in Europe and the United States. Whereas receiving breastfeeding, evidence of a Helicobacter pylori infection and vitamin D are important protective factors in Crohn’s disease as well as ulcerative colitis, increased hygiene, experiencing a bacterial gastroenteritis in the past, urban living surroundings, air pollution, the use of antibiotics, nonsteroidal anti-inflammatory drugs, and oral contraceptives are likely to be the most important risk factors for both diseases. Current cigarette smoking yields a divergent effect by protecting against ulcerative colitis but increasing risk of Crohn’s disease, whereas former smoking increases chances of both diseases. This review gives a clear overview of the current state of knowledge concerning the exposome. Future studies should focus on measuring this exposome yielding the possibility of combining all involved factors to one exposome risk score and our knowledge on genetic susceptibility.

PMID: 28777099 [PubMed – as supplied by publisher]

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Evidence-based clinical guidelines for eating disorders: international comparison.

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Evidence-based clinical guidelines for eating disorders: international comparison.

Curr Opin Psychiatry. 2017 Aug 01;:

Authors: Hilbert A, Hoek H, Schmidt R

Abstract
PURPOSE OF REVIEW: The current systematic review sought to compare available evidence-based clinical treatment guidelines for all specific eating disorders.
RECENT FINDINGS: Nine evidence-based clinical treatment guidelines for eating disorders were located through a systematic search. The international comparison demonstrated notable commonalities and differences among these current clinical guidelines. Consistency across guidelines was greatest for treatments with a larger evidence base, while those with a lower evidence base had recommendations that varied considerably.
SUMMARY: Evidence-based clinical guidelines represent an important step toward the dissemination and implementation of evidence-based treatments into clinical practice. Despite advances in clinical research on eating disorders, a growing body of literature demonstrates that individuals with eating disorders often do not receive an evidence-based treatment for their disorder. Regarding the dissemination and implementation of evidence-based treatments, current guidelines do endorse the main empirically validated treatment approaches with considerable agreement, but additional recommendations are largely inconsistent. An increased evidence base is critical in offering clinically useful and reliable guidance for the treatment of eating disorders. Because developing and updating clinical guidelines is time-consuming and complex, an international coordination of guideline development, for example, across the European Union, would be desirable.

PMID: 28777107 [PubMed – as supplied by publisher]

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Maternal occupational exposure and oral clefts in offspring

Maternal occupational exposure and oral clefts in offspring

Spinder, N., Bergman, J. E. H., Boezen, H. M., Vermeulen, R. C. H., Kromhout, H. & de Walle, H. E. K. 4-Aug-2017 In : Environmental health. 16, 11 p., 83

Research output: Scientific – peer-reviewArticle

Original language English
Article number 83
Number of pages 11
Journal Environmental health
Volume 16
State Published – 4-Aug-2017
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Revealing Oft-cited but Unpublished Papers of Colin Pittendrigh and Coworkers.

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Revealing Oft-cited but Unpublished Papers of Colin Pittendrigh and Coworkers.

J Biol Rhythms. 2017 Jul 01;:748730417716685

Authors: Tackenberg MC, Johnson CH, Page TL, Daan S

Abstract
Among the scientific resources that Colin Pittendrigh passed on to his colleagues after his death in 1996 were two unpublished papers. These manuscripts, developed first in the mid-1960s and continually updated and refined through the late 1970s, centered on the development and experimental exploration of a model of circadian entrainment combining aspects of the well-known parametric (continuous) and nonparametric (discrete) models of entrainment. These texts reveal the experimental work surrounding Pittendrigh’s determination of the limits of entrainment and the explanation of the bistability phenomenon. These manuscripts are being made publicly available in their final format (February 1978) as supplementary material to this introduction.

PMID: 28766460 [PubMed – as supplied by publisher]

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Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2.

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Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2.

Structure. 2017 Aug 01;25(8):1163-1174

Authors: Zak KM, Grudnik P, Magiera K, Dömling A, Dubin G, Holak TA

Abstract
Cancer cells can avoid and suppress immune responses through activation of inhibitory immune checkpoint proteins, such as PD-1, PD-L1, and CTLA-4. Blocking the activities of these proteins with monoclonal antibodies, and thus restoring T cell function, has delivered breakthrough therapies against cancer. In this review, we describe the latest work on structural characterization of the checkpoint proteins, their interactions with cognate ligands and with therapeutic antibodies. Structures of the extracellular portions of these proteins reveal that they all have a similar modular structure, composed of small domains similar in topology to the domains found in antibodies. Structural basis for blocking the PD-1/PD-L1 interaction by small molecules is illustrated with the compound BMS-202 that binds to and induces dimerization of PD-L1.

PMID: 28768162 [PubMed – in process]

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A sharp Pif1-dependent threshold separates DNA double-strand breaks from critically short telomeres

A sharp Pif1-dependent threshold separates DNA double-strand breaks from critically short telomeres

Strecker, J., Stinus, S., Caballero, M. P., Szilard, R. K., Chang, M. & Durocher, D. 3-Aug-2017 In : eLife. 6, 59 p.

Research output: Scientific – peer-reviewArticle

Original language English
Number of pages 59
Journal eLife
Volume 6
State Published – 3-Aug-2017
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Influence of biofilm lubricity on shear-induced transmission of staphylococcal biofilms from stainless steel to silicone rubber

Original language English
Journal Microbial Biotechnology
State E-pub ahead of print – 3-Aug-2017
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Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress

Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress

van Gisbergen, M. W., Voets, A. M., Biemans, R., Hoffmann, R. F., Drittij-Reijnders, M-J., Haenen, G. R. M. M., Heijink, I. H., Rouschop, K. M. A., Dubois, L. J. & Lambin, P. 3-Aug-2017 In : Plos one. 12, 8, 13 p., 0182508

Research output: Scientific – peer-reviewArticle

Original language English
Article number 0182508
Number of pages 13
Journal Plos one
Volume 12
Issue number 8
State Published – 3-Aug-2017
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Serotonin Transporter Genotype Modulates the Gut Microbiota Composition in Young Rats, an Effect Augmented by Early Life Stress

Original language English
Article number 222
Number of pages 12
Journal Frontiers in cellular neuroscience
Volume 11
State Published – 3-Aug-2017
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Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia

Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia

Berhe, D., Taxis, K., Ruskamp, F., Mulugeta, A., Mengistu, Y. T. & Mol, P. G. M. 3-Aug-2017 In : BMJ Open. 7, 12 p., e015743

Research output: Scientific – peer-reviewArticle

Original language English
Article number e015743
Number of pages 12
Journal BMJ Open
Volume 7
State Published – 3-Aug-2017
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Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia

Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia

Berhe, D., Taxis, K., Ruskamp, F., Mulugeta, A., Mengistu, Y. T. & Mol, P. G. M. 3-Aug-2017 In : BMJ Open. 7, e015743.

Research output: Scientific – peer-reviewArticle

Original language English
Journal BMJ Open
Volume 7
Issue number e015743.
State Published – 3-Aug-2017
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Interim FDG-PET in lymphoma, a questionable practice in hematology.

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Interim FDG-PET in lymphoma, a questionable practice in hematology.

Eur J Nucl Med Mol Imaging. 2017 Jul 31;:

Authors: Adams HJA, Kwee TC

PMID: 28761975 [PubMed – as supplied by publisher]

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Capecitabine, 5-fluorouracil and S-1 based regimens for previously untreated advanced oesophagogastric cancer: A network meta-analysis

Capecitabine, 5-fluorouracil and S-1 based regimens for previously untreated advanced oesophagogastric cancer: A network meta-analysis

ter Veer, E., Ngai, L. L., van Valkenhoef, G., Mohammad, N. H., Anderegg, M. C. J., van Oijen, M. G. H. & van Laarhoven, H. W. M. 2-Aug-2017 In : Scientific Reports. 7, 8 p., 7142

Research output: Scientific – peer-reviewArticle

Original language English
Article number 7142
Number of pages 8
Journal Scientific Reports
Volume 7
State Published – 2-Aug-2017
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Preventing musculoskeletal injuries among recreational adult volleyball players: design of a randomised prospective controlled trial

Preventing musculoskeletal injuries among recreational adult volleyball players: design of a randomised prospective controlled trial

Gouttebarge, V., Zwerver, J. & Verhagen, E. 2-Aug-2017 In : Bmc Musculoskeletal Disorders. 18, 1, p. 333

Research output: Scientific – peer-reviewArticle

Original language English
Pages (from-to) 333
Journal Bmc Musculoskeletal Disorders
Volume 18
Issue number 1
State Published – 2-Aug-2017
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Management of device-related malignant sarcoma

Management of device-related malignant sarcoma

Khamooshian, A., Klinkenberg, T. J., Maass, A. H. & Mariani, M. A. Aug-2017 In : HeartRhythm case reports. 3, 8, p. 373-376 4 p.

Research output: Scientific – peer-reviewArticle

Original language English
Pages (from-to) 373-376
Number of pages 4
Journal HeartRhythm case reports
Volume 3
Issue number 8
State Published – Aug-2017
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Motor learning strategies in basketball players and its implications for ACL injury prevention: a randomized controlled trial

Original language English
Pages (from-to) 2365-2376
Number of pages 12
Journal Knee surgery sports traumatology arthroscopy
Volume 25
Issue number 8
State Published – Aug-2017
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