Evaluation of a Culture-Dependent Algorithm and a Molecular Algorithm for Identification of Shigella spp., Escherichia coli, and Enteroinvasive E. coli

Evaluation of a Culture-Dependent Algorithm and a Molecular Algorithm for Identification of Shigella spp., Escherichia coli, and Enteroinvasive E. coli

van den Beld, M. J. C., de Boer, R. F., Reubsaet, F. A. G., Rossen, J. W. A., Zhou, K., Kuiling, S., Friedrich, A. W. & Kooistra-Smidb, M. A. M. D. Oct-2018 In : Journal of Clinical Microbiology. 56, 10, 13 p., e00510-18

Research output: Contribution to journalArticle

Original language English
Article number e00510-18
Number of pages 13
Journal Journal of Clinical Microbiology
Volume 56
Issue number 10
State Published – Oct-2018
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The efficacy of ultrasound in the follow up after a negative sentinel lymph node in women with vulvar cancer: a prospective single-centre study

The efficacy of ultrasound in the follow up after a negative sentinel lymph node in women with vulvar cancer: a prospective single-centre study

Pouwer, A. W., Mus, R. D. M., IntHout, J., van der Zee, A. G. J., Bulten, J., Massuger, L. F. A. G. & de Hullu, J. A. Oct-2018 In : BJOG-an International Journal Of Obstetrics And Gynaecology. 125, 11, p. 1461-1468 8 p.

Research output: Contribution to journalArticle

Original language English
Pages (from-to) 1461-1468
Number of pages 8
Journal BJOG-an International Journal Of Obstetrics And Gynaecology
Volume 125
Issue number 11
State Published – Oct-2018
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How to … choose between different types of data

How to … choose between different types of data

Helmich, E., Stenfors, T. & Barrett, A. Oct-2018 In : Clinical teacher. 15, 5, p. 366-369 4 p.

Research output: Contribution to journalArticle

Original language English
Pages (from-to) 366-369
Number of pages 4
Journal Clinical teacher
Volume 15
Issue number 5
State Published – Oct-2018
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Sepsis patients in the emergency department: Stratification using the Clinical Impression Score, Predisposition, Infection, Response and Organ dysfunction score or quick Sequential Organ Failure Assessment score?

Original language English
Pages (from-to) 328-334
Number of pages 7
Journal European journal of emergency medicine
Volume 25
Issue number 5
State Published – Oct-2018
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Noninvasive intracranial pressure assessment using otoacoustic emissions: An application in glaucoma

Original language English
Article number e0204939
Number of pages 11
Journal PLoS ONE
Volume 13
Issue number 10
State Published – Oct-2018
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Measurement properties of the Dutch Unite Rhumatologique des Affections de la Main and its ability to measure change due to Dupuytren’s disease progression compared with the Michigan Hand outcomes Questionnaire

Original language English
Pages (from-to) 855-863
Number of pages 9
Journal Journal of Hand Surgery (European volume)
Volume 43
Issue number 8
State Published – Oct-2018
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Appropriate use criteria for optical coherence tomography guidance in percutaneous coronary interventions Recommendations of the working group of interventional cardiology of the Netherlands Society of Cardiology

Appropriate use criteria for optical coherence tomography guidance in percutaneous coronary interventions Recommendations of the working group of interventional cardiology of the Netherlands Society of Cardiology

IJsselmuiden, A. J. J., Zwaan, E. M., Oemrawsingh, R. M., Bom, M. J., Dankers, F. J. W. M., de Boer, M. J., Camaro, C., van Geuns, R. J. M., Daemen, J., van der Heijden, D. J., Jukema, J. W., Kraaijeveld, A. O., Meuwissen, M., Scholzel, B. E., Pundziute, G., van der Harst, P., van Ramshorst, J., Dirksen, M. T., Zivelonghi, C., Agostoni, P., van der Heyden, J. A. S., Wykrzykowska, J. J., Scholte, M. J., Nef, H. M., Kofflard, M. J. M., van Royen, N., Alings, M. & Kedhi, E. Oct-2018 In : Netherlands Heart Hournal. 26, 10, p. 473-483 11 p.

Research output: Contribution to journalReview article

Original language English
Pages (from-to) 473-483
Number of pages 11
Journal Netherlands Heart Hournal
Volume 26
Issue number 10
State Published – Oct-2018
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Altered movement during single leg hop test after ACL reconstruction: implications to incorporate 2-D video movement analysis for hop tests

Original language English
Pages (from-to) 3012-3019
Number of pages 8
Journal Knee Surgery Sports Traumatology Arthroscopy
Volume 26
Issue number 10
State Published – Oct-2018
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Diagnosis and management of Cornelia de Lange syndrome: first international consensus statement

Diagnosis and management of Cornelia de Lange syndrome: first international consensus statement

Kline, A. D., Moss, J. F., Selicorni, A., Bisgaard, A-M., Deardorff, M. A., Gillett, P. M., Ishman, S. L., Kerr, L. M., Levin, A. V., Mulder, P. A., Ramos, F. J., Wierzba, J., Ajmone, P. F., Axtell, D., Blagowidow, N., Cereda, A., Costantino, A., Cormier-Daire, V., FitzPatrick, D., Grados, M., Groves, L., Guthrie, W., Huisman, S., Kaiser, F. J., Koekkoek, G., Levis, M., Mariani, M., McCleery, J. P., Menke, L. A., Metrena, A., O’Connor, J., Oliver, C., Pie, J., Piening, S., Potter, C. J., Quaglio, A. L., Redeker, E., Richman, D., Rigamonti, C., Shi, A., Tumer, Z., Van Balkom, I. D. C. & Hennekam, R. C. Oct-2018 In : Nature Reviews Genetics. 19, 10, p. 649-666 18 p.

Research output: Contribution to journalReview article

Original language English
Pages (from-to) 649-666
Number of pages 18
Journal Nature Reviews Genetics
Volume 19
Issue number 10
State Published – Oct-2018
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Radiofrequency ablation in the treatment of atypical cartilaginous tumours in the long bones: Lessons learned from our experience

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Myocardial bridging of the left anterior descending coronary artery is associated with reduced myocardial perfusion reserve: A N-ammonia PET study

Myocardial bridging of the left anterior descending coronary artery is associated with reduced myocardial perfusion reserve: A N-ammonia PET study

Monroy-Gonzalez, A. G., Alexanderson-Rosas, E., Prakken, N. H. J., Juarez-Orozco, L. E., Walls-Laguarda, L., Berrios-Barcenas, E. A., Meave-Gonzalez, A., Groot, J. C., Slart, R. H. J. A. & Tio, R. A. 28-Sep-2018 In : International Journal Of Cardiovascular Imaging. 8 p.

Research output: Contribution to journalArticle

Original language English
Number of pages 8
Journal International Journal Of Cardiovascular Imaging
State Published – 28-Sep-2018
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Antimicrobial Resistance in Class 1 Integron-Positive Shiga Toxin-Producing Isolated from Cattle, Pigs, Food and Farm Environment

Antimicrobial Resistance in Class 1 Integron-Positive Shiga Toxin-Producing Isolated from Cattle, Pigs, Food and Farm Environment

Colello, R., Krüger, A., Conza, J. D., Rossen, J. W. A., Friedrich, A. W., Gutkind, G., Etcheverría, A. I. & Padola, N. L. 28-Sep-2018 In : Microorganisms. 6, 4, 8 p.

Research output: Contribution to journalArticle

Original language English
Number of pages 8
Journal Microorganisms
Volume 6
Issue number 4
State Published – 28-Sep-2018
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Development of a thermostable spray dried outer membrane vesicle pertussis vaccine for pulmonary immunization

Development of a thermostable spray dried outer membrane vesicle pertussis vaccine for pulmonary immunization

Kanojia, G., Raeven, R. H. M., van der Maas, L., Bindels, T. H. E., van Riet, E., Metz, B., Soema, P. C., Ten Have, R., Frijlink, H. W., Amorij, J-P. & Kersten, G. F. A. 24-Jul-2018 In : Journal of controlled release : official journal of the Controlled Release Society. 286, p. 167-178 12 p.

Research output: Contribution to journalArticle

Original language English
Pages (from-to) 167-178
Number of pages 12
Journal Journal of controlled release : official journal of the Controlled Release Society
Volume 286
Early online date 24-Jul-2018
State E-pub ahead of print – 24-Jul-2018
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Detecting the Dependence of Diversification on Multiple Traits from Phylogenetic Trees and Trait Data.

Detecting the Dependence of Diversification on Multiple Traits from Phylogenetic Trees and Trait Data.

Syst Biol. 2018 Sep 26;:

Authors: Herrera-Alsina L, van Els P, Etienne RS

Abstract
Species diversification may be determined by many different variables, including the traits of the diversifying lineages. The State-dependent Speciation and Extinction (SSE) framework contains methods to detect the dependence of diversification on these traits. For the analysis of traits with multiple states, MuSSE (Multiple-States dependent Speciation and Extinction) was developed. However, MuSSE and other state-dependent speciation and extinction models have been shown to yield false positives, because they cannot separate differential diversification rates from dependence of diversification on the observed traits. The recently introduced method HiSSE (Hidden- State dependent Speciation and Extinction) resolves this problem by allowing a hidden state to affect diversification rates. Unfortunately, HiSSE does not allow traits with more than two states, and, perhaps more interestingly, the simultaneous action of multiple traits on diversification. Here, we introduce an R package (SecSSE: Several examined and concealed States-dependent Speciation and Extinction) that combines the features of HiSSE and MuSSE to simultaneously infer state-dependent diversification across two or more examined (observed) traits or states while accounting for the role of a possible concealed (hidden) trait. Moreover, SecSSE also has improved functionality compared to its two ‘parents’. First, it allows for an observed trait being in two or more states simultaneously, which is useful for example when a taxon is a generalist or when the exact state is not precisely known. Second, it provides the correct likelihood when conditioned on non-extinction, which has been incorrectly implemented in HiSSE and other SSE models. To illustrate our method we apply SecSSE to 7 previous studies that used MuSSE, and find that in 5 out of 7 cases, the conclusions drawn based on MuSSE were premature. We test with simulations whether SecSSE sacrifices statistical power to avoid the high type I error problem of MuSSE, but we find that this is not the case: for the majority of simulations where the observed traits affect diversification, SecSSE detects this.

PMID: 30257005 [PubMed – as supplied by publisher]

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De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis.

De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis.

Cell Rep. 2018 Sep 25;24(13):3441-3454.e12

Authors: Wang S, Mandell JD, Kumar Y, Sun N, Morris MT, Arbelaez J, Nasello C, Dong S, Duhn C, Zhao X, Yang Z, Padmanabhuni SS, Yu D, King RA, Dietrich A, Khalifa N, Dahl N, Huang AY, Neale BM, Coppola G, Mathews CA, Scharf JM, Tourette International Collaborative Genetics Study (TIC Genetics), Tourette Syndrome Genetics Southern and Eastern Europe Initiative (TSGENESEE), Tourette Association of America International Consortium for Genetics (TAAICG), Fernandez TV, Buxbaum JD, De Rubeis S, Grice DE, Xing J, Heiman GA, Tischfield JA, Paschou P, Willsey AJ, State MW

Abstract
We previously established the contribution of de novo damaging sequence variants to Tourette disorder (TD) through whole-exome sequencing of 511 trios. Here, we sequence an additional 291 TD trios and analyze the combined set of 802 trios. We observe an overrepresentation of de novo damaging variants in simplex, but not multiplex, families; we identify a high-confidence TD risk gene, CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3); we find that the genes mutated in TD patients are enriched for those related to cell polarity, suggesting a common pathway underlying pathobiology; and we confirm a statistically significant excess of de novo copy number variants in TD. Finally, we identify significant overlap of de novo sequence variants between TD and obsessive-compulsive disorder and de novo copy number variants between TD and autism spectrum disorder, consistent with shared genetic risk.

PMID: 30257206 [PubMed – in process]

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Diagnostic stewardship: zin of onzin?!

Translated title of the contribution Diagnostic stewardship: sense or nonsense?!
Original language Dutch
Journal Nederlands Tijdschrift voor Medische Microbiologie
Volume 26
Issue number 3
State Published – 27-Sep-2018
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The impact of CYP2D6 mediated drug-drug interaction: a systematic review on a combination of metoprolol and paroxetine/fluoxetine.

Related Articles

The impact of CYP2D6 mediated drug-drug interaction: a systematic review on a combination of metoprolol and paroxetine/fluoxetine.

Br J Clin Pharmacol. 2018 Sep 24;:

Authors: Bahar MA, Kamp J, Borgsteede SD, Hak E, Wilffert B

Abstract
AIM: Metoprolol (a CYP2D6 substrate) is often co-prescribed with paroxetine/fluoxetine (a CYP2D6 inhibitor) because the clinical relevance of this drug-drug interaction (DDI) is still unclear. This review aimed to systematically evaluate the available evidence and quantify the clinical impact of the DDI.
METHOD: Pubmed, Web of Science, Cochrane Library and Embase were searched for studies reporting on the effect of the DDI among adults published until April 2018. Data on pharmacokinetics, pharmacodynamics and clinical outcomes from experimental, observational and case report studies were retrieved. The protocol of this study was registered in PROSPERO (CRD42018093087).
RESULTS: We found nine eligible articles that consisted of four experimental and two observational studies as well as three case reports. Experimental studies reported that paroxetine increased the AUC of metoprolol three to five times, and significantly decreased systolic blood pressure and heart rate of patients. Case reports concerned bradycardia and atrioventricular block due to the DDI. Results from observational studies were conflicting. A cohort study indicated that the DDI was significantly associated with the incidence of early discontinuation of metoprolol as an indicator of the emergence of metoprolol-related side effects. In a case-control study, the DDI was not significantly associated with bradycardia.
CONCLUSION: Despite the contradictory conclusions from the current literature, the majority of studies suggest that the DDI can lead to adverse clinical consequences. Since alternative antidepressants and beta-blockers with comparable efficacy are available, such DDIs can be avoided. Nonetheless, if prescribing the combination is unavoidable, a dose adjustment or close monitoring of the metoprolol-related side effects is necessary.

PMID: 30248178 [PubMed – as supplied by publisher]

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When we document end-of-life care, words still matter.

Related Articles

When we document end-of-life care, words still matter.

J Pain Symptom Manage. 2018 Sep 21;:

Authors: Kelemen A, Groninger H

PMID: 30248385 [PubMed – as supplied by publisher]

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Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts

Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts

Schuliga, M., Pechkovsky, D. V., Read, J., Waters, D. W., Blokland, K. E. C., Reid, A. T., Hogaboam, C. M., Khalil, N., Burgess, J. K., Prêle, C. M., Mutsaers, S. E., Jaffar, J., Westall, G., Grainge, C. & Knight, D. A. 26-Sep-2018 In : Journal of cellular and molecular medicine. 15 p.

Research output: Contribution to journalArticle

Original language English
Number of pages 15
Journal Journal of cellular and molecular medicine
State Published – 26-Sep-2018
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Hallucinaties beter in beeld met fMRI

​Jasper Looijestijn: Exploring function in the hallucinating brain Met nieuwe analysetechnieken is het mogelijk om het ontstaan van hallucinaties in …

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