Anthony Absalom – F1000 Faculty Member (since 11 June 2009)

Department of Anaesthesiology, University Medical Center Groningen, Groningen, Netherlands

BIOGRAPHY

ACADEMIC POSITION:
Professor of Anesthesia, University Medical Center Groningen, University of Groningen

EDUCATION:
University of Cape Town

MEMBERSHIPS:
• American Society of Anesthesiologists (ASA)
• Board member of ISAP (International Society for Anaesthetic Pharmacology)
• Honorary Treasurer of UK Society for Intravenous Anaesthesia
• Board member, British Journal of Anaesthesia
• Board Member, Trends in Anaesthesia and Critical Care

RESEARCH INTERESTS:
Pharmacology, neuroscience.

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Henk Groen – F1000 Associate Faculty Member (since 21 April 2010)

Department of Epidemiology, University Medical Center Groningen, Groningen, Netherlands

BIOGRAPHY

Henk Groen is an Associate Faculty Member who works with Erik Buskens to evaluate the literature relevant to their research interests.Henk Groen also has responsibility for checking the contents of the following journals to ensure that the highest quality research relevant to their own interests within these publications is comprehensively and systematically evaluated for F1000:- International Journal of EpidemiologyCURRENT POSITION:
• Epidemiologist/HTA researcher, Department of Epidemiology, University Medical Center Groningen, University of GroningenEDUCATION:
• MD University of Groningen, October 1987
• PhD University of Groningen, April 1993
• EpidemiologistMEMBERSHIPS:
• Health Technology Assessment International (HTAi)
• Dutch Society for Epidemiology (VVE)
• Dutch Society for Technology Assessment in Healthcare (NVTAG)RESEARCH INTERESTS:
• Perinatal epidemiology
• Fertility medicine
• Obstetrics & gynaecology
• Prediction models
• Cost-effectiveness

Behrooz Alizadeh – F1000 Associate Faculty Member (since 17 October 2011)

Department of Epidemiology, University Medical Center Groningen, Groningen, Netherlands

BIOGRAPHY

Behrooz Alizadeh is an Associate Faculty Member who works with Harold Snieder to evaluate the literature relevant to their research interests.

Herman Meurs – F1000 Faculty Member (since 02 November 2010)

Department of Molecular Pharmacology, University of Groningen, Groningen, Netherlands

BIOGRAPHY

ACADEMIC POSITION:
Herman Meurs is Professor of Immunopharmacology and head of the Department of Molecular Pharmacology at the University Centre for Pharmacy in Groningen.QUALIFICATION:
PhDRESEARCH INTERESTS:
His major research interests are the (immunological) regulation mechanisms of airway smooth muscle function, with particular focus on the pathophysiology of asthma and COPD using various animal-, tissue- and cellular model systems. His research is aimed at the development of novel pharmacotherapeutic treatments of these diseases.

Erik Buskens – F1000 Faculty Member (since 11 November 2005)

Department of Epidemiology, University Medical Center Groningen, Groningen, Netherlands

BIOGRAPHY

ACADEMIC POSITION:
Professor of Medical Technology Assessment, University Medical Center GroningenEDUCATION:
Medical degree obtained in RotterdamMEMBERSHIPS/AWARDS:
• Current chair of the board of the NVTAG
• Member of several national and international committees and bodies on MTA and the role thereof in guidelines and policy makingRESEARCH INTERESTS:
His primary fields of interest have been cerebrovascular diseases and mathematical disease modelling.

Dirk-Jan Slotboom – F1000 Associate Faculty Member (since 15 December 2010)

Department of Biochemistry, University of Groningen, Groningen, Netherlands

BIOGRAPHY

Dirk-Jan Slotboom is an Associate Faculty Member who works with Bert Poolman to evaluate the literature relevant to their research interests.

Cees Kallenberg – F1000 Faculty Member (since 15 October 2008)

Department of Rheumatology and Clinical Immunology, University Medical Center Groningen,Groningen, Netherlands

BIOGRAPHY

ACADEMIC POSITION:
Professor, Department of Rheumatology and Clinical Immunology, University Medical Center GroningenEDUCATION:
Cees GM Kallenberg got his medical training at the Medical School of the University of Leiden, The Netherlands. After getting his degree as an MD in 1972, he got additional training in surgery and served as a military MD in the Dutch Army. In 1975 he started his training as a resident in Internal Medicine at the Groningen University Hospital and was registered as internist in 1980. He worked as an internist and finished his PhD studies on the subject ‘Raynaud’s phenomenon and Systemic Autoimmune Disease’ successfully in 1982. He further trained in immunology and medical immunology and was registered as immunologist and medical immunologist. He was appointed as associate professor in Internal Medicine – Clinical Immunology in 1985 and as a full professor in 1993.AUTHORSHIP/EDITORIAL:
He has written more than 300 articles in international peer-reviewed journals, gives lectures as an invited speaker on his research topics on all major international meetings, and is an editorial board member of several journals in clinical immunology, nephrology and rheumatology.RESEARCH INTERESTS:
Systemic auto-immune diseases; immunodeficiencies.

BIOGRAPHY

Alain Kalmar is an Associate Faculty Member who works with Anthony Absalom to evaluate the literature relevant to their research interests.EDUCATION:
2011 PhD, University Medical Centre GroningenRESEARCH PROJECT:
New surgical treatment options, such as endoscopic neurosurgery, require adequate monitoring and management of the intracranial pressure, cerebral oxygenation and homeostasis. In his PhD thesis a new methodology is described that significantly improves perioperative monitoring.Endoscopic neurosurgical procedures may result in increased intracranial pressure and acute hemodynamic effects. It was shown that the initial phase of this so called Cushing reflex consists of a combination of hypertension and tachycardia. These clinical findings were confirmed in a rat-model of endoscopic neurosurgery, which resulted in the investigation of various methods to monitor the Cushing reflex. The newly developed method is significantly more precise as compared to the present approach.

Reinoud Gosens – F1000 Associate Faculty Member (since 20 July 2011)

Faculty of Mathematics and Natural Sciences, University of Groningen, Groningen, Netherlands

BIOGRAPHY

Reinoud Gosens is an Associate Faculty Member who works with Herman Meurs to evaluate the literature relevant to their research interests.Reinoud Gosens also has responsibility for checking the contents of the following journals to ensure that the highest quality research relevant to their own interests within these publications is comprehensively and systematically evaluated for F1000:- The Journal of Clinical Investigation
– PloS One

Loes Kistemaker – F1000 Associate Faculty Member (since 08 July 2011)

Molecular Pharmacology Department, University of Groningen, Groningen,, Netherlands

BIOGRAPHY

Loes Kistemaker is an Associate Faculty Member who works with Herman Meurs to evaluate the literature relevant to their research interests.Loes Kistemaker also has responsibility for checking the contents of the following journals to ensure that the highest quality research relevant to their own interests within these publications is comprehensively and systematically evaluated for F1000:- The New England Journal of Medicine
– American Journal of Respiratory and Critical Care Medicine

BIOGRAPHY

Marko Sahinovic is an Associate Faculty Member who works with Anthony Absalom to evaluate the literature relevant to their research interests.RESEARCH INTERESTS:
Marko Sahinovic works with Anthony Absalom who is part of a group of investigators who are interested in mechanisms of anaesthetic and sedative drug action, and also consciousness itself.

Jurjen Oosterhuis – F1000 Associate Faculty Member (since 16 August 2010)

Department of Anesthesiology, University Medical Center Groningen, Groningen, Netherlands

BIOGRAPHY

Jurjen Oosterhuis is an Associate Faculty Member who works with Anthony Absalom to evaluate the literature relevant to their research interests.RESEARCH INTERESTS:
Jurjen Oosterhuis works with Anthony Absalom who is part of a group of investigators who are interested in mechanisms of anaesthetic and sedative drug action, and also consciousness itself.

Cees Smit Sibinga – F1000 Faculty Member (since 20 January 2006)

Aula Academiegebouw Rijksuniversiteit,, University of Groningen, Groningen, Netherlands

BIOGRAPHY

Cees Th. Smit Sibinga, MDAcademic positions:
– Professor of International Development of Transfusion Medicine at the Faculty of Medical Sciences, University of Groningen
– Dr. Smit Sibinga was the founder and first Director of the Academic Institute for International Development of Transfusion Medicine (IDTM)
– Dr Smit Sibinga was medical director of the Regional Blood Bank Noord Nederland (1976-2001) which he created and extended into a well respected international centre of excellence. The centre was assigned the status of WHO Collaborating Centre for Blood Transfusion (1993), WFH International Hemophilia Training Centre (1993) and ICBS Collaborating Centre (2001) and hosted numerous international fellows for training.
He is a long term transfusion medicine expert member of the WHO Expert Committee of Blood Transfusion and is currently the acting Director of ID Consulting for International Development of Transfusion Medicine (www.idconsulting.info) and involved numerous international transfusion medicine development projects and programs.All industry positions (in last five years):
– Dr. Smit Sibinga was the founder and first Director of the Sanquin Consulting Services (SCS) and vice-president/director of the AABB Consulting Services Division.Research interests: hematology, blood coagulation, transfusion medicine and quality managementAny other information:
Dr Smit Sibinga became a Fellow of Transfusion Medicine at the Royal College of Physicians of Edinburgh (1992) and Royal College of Pathologists London (1995). He has been the initiator and organizer of 28 consecutive and internationally reputed and respected Symposia on Blood Transfusion in Groningen. He published over 300 peer reviewed articles and book chapters on hemostasis and transfusion medicine and edited over 30 books in his field.

Jana van Vliet-Ostaptchouk – F1000 Associate Faculty Member (since 10 October 2011)

Department of Endocrinology, University Medical Center Groningen, Groningen, Netherlands

BIOGRAPHY

Jana van Vliet is an Associate Faculty Member who works with Harold Snieder to evaluate the literature relevant to their research interests.Jana also has the responsibility for checking the contents of the following journals to ensure that the highest quality research relevant to their own interests within these publications is comprehensively and systematically evaluated for F1000:- Diabetes
– Nature GeneticsCURRENT POSITION
Jana van Vliet-Ostaptchouk is a postdoctoral fellow at the Department of Endocrinology (headed by Professor Bruce Wolffenbuttel) with a 2nd affiliation at the Department of Epidemiology (Professor Harold Snieder’s group), at the University Medical Center Groningen, the Netherlands.EDUCATION AND BACKGROUND
Jana van Vliet obtained her MSc degree in Physiology at Novosibirsk State University, Russia (1995). Her Master’s thesis under the supervision of Professor Arkady L Markel (Institute of Cytology and Genetics, Russian Academy of Science, Novosibirsk) was based on research on the genetics of essential hypertension. In 2010, she obtained a PhD degree at the University Medical Center Groningen, the Netherlands. The project ‘Revealing the genetic roots of obesity and type 2 diabetes’ was supervised by Professor Marten Hofker and Professor Cisca Wijmenga. In that same year Jana received a Rubicon fellowship from the Netherlands Organization for Scientific Research to work as a visiting scientist at Dr Ruth Loos’ group at the MRC Epidemiology Unit in Cambridge, UK. The research is focused on the examination of the pleiotropic effects of the currently established obesity-susceptibility loci on metabolic traits.RESEARCH AREA:
Jana van Vliet is a human geneticist with specific expertise in obesity and type 2 diabetes.RESEARCH INTERESTS
The complex nature of obesity and type 2 diabetes is the main scientific interest of Jana van Vliet. In her current research she investigates how environmental factors together with genetic factors influence the disease etiology with a particular interest in gene-gene and gene-environmental interactions. A focus of this latter objective is to study whether DNA methylation changes may have important epigenetic mechanisms linking the responses to environmental factors and obesity. These questions are addressed within the National Consortium of Healthy Aging using LifeLines data, a large three-generations longitudinal population-based study, and through international collaborations.

Harold Snieder – F1000 Faculty Member (since 11 November 2010)

Department of Epidemiology, University Medical Center Groningen, Groningen, Netherlands

BIOGRAPHY

ACADEMIC POSITION:
In November 2006 he became head of the Genetic Epidemiology and Bioinformatics Unit in the Department of Epidemiology, University Medical Center Groningen.EDUCATION AND BACKGROUND:
He did an MSc in exercise physiology and psychology at the VU University, Amsterdam, and his PhD project on the ‘Genetic epidemiology of risk factors of cardiovascular disease. A study of middle-aged twins’ was supervised by Lorenz van Doornen (psychophysiology) and Dorret Boomsma (behavior genetics) at the VU University and completed in 1996. He then joined Tim Spector’s group at the Twin Research & Genetic Epidemiology Unit, St Thomas’ Hospital, London, to study the genetic epidemiology of common complex traits with a main focus on cardiovascular disease and making use of linkage and association approaches. In October 2000 he moved to the Medical College of Georgia in Augusta, Georgia, where he joined Frank Treiber’s multidisciplinary research institute (the Georgia Prevention Institute) to study genetic risk factors in interaction with behavioral and environmental antecedents of cardiovascular disease in youth. There he worked on a fifteen year longitudinal cohort study in Georgia. He was awarded tenure on 1 July 2005, and in December 2005 he was granted a joint appointment at the Department of Biostatistics.FUNDING:
His work has been funded by the British and American Heart Foundations, The Wellcome Trust, and the National Heart, Lung, and Blood Institute (NIH).RESEARCH AREA:
Harold Snieder is a genetic epidemiologist with specific expertise in cardiovascular disease, obesity and type 2 diabetes.Further information can be found at: http://www.rug.nl/umcg/faculteit/disciplinegroepen/epidemiologie/snieder

Bert Poolman – F1000 Faculty Member (since 29 October 2010)

Department of Biochemistry, University of Groningen, Groningen, Netherlands

BIOGRAPHY

ACADEMIC POSITION:
Bert Poolman is Professor in Biochemistry and Program Director of the Centre for Synthetic Biology.

MEMBERSHIPS:
He is a member of the Royal Netherlands Academy of Arts and Sciences (KNAW).

RESEARCH INTERESTS:
His research focuses on the elucidation of the mechanisms by which signals are transduced and small molecules are translocated across cellular membranes. Cells are reengineered for the production of correctly folded membrane proteins, and methods are developed to reconstitute complex molecular assemblies in synthetic membranes and to analyze their functional and structural properties. The in vitro mechanistic studies are used to strengthen in vivo physiological measurements and vice versa.

Research topics in his group include:
(i) the mechanisms of translocation catalysis by ATP-binding cassette transporters;
(ii) the molecular basis of cell volume regulation, including a comprehensive understanding of the role of lipid-protein interactions, (macro)molecular crowding and other generic physicochemical factors in transmembrane signaling and transport; and
(iii) membrane proteomics with a focus on nuclear and vacuolar membranes and the basis for molecule transport through the nuclear pore complex.

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Ton Lisman – F1000 Faculty Member (since 04 February 2011)

Surgical Research Laboratory, Department of Surgery, University Medical Center Groningen,Groningen, Netherlands

BIOGRAPHY

ACADEMIC POSITION:
Adjunct (associate) Professor of Experimental Surgery, Surgical Research Laboratory, Department of Surgery, University Medical Center Groningen, The Netherlands

EDUCATION:
• 2002 PhD, Thrombosis and Haemostasis Laboratory, University Medical Center Utrecht, The Netherlands. Title of dissertation: Haemostatic effects of recombinant factor VIIa. Supervisors: Prof Dr PhG de Groot, Dr HK Nieuwenhuis
• 1994-1998 Master of Science training program, Chemistry Faculty, Utrecht University, The Netherlands

RESEARCH INTERESTS:
The research line led by biochemist Prof Dr Ton Lisman and surgeon Prof Dr Robert J Porte focuses on clinically oriented questions on the intersection of hematology and hepatology. Combining expertise in basal biochemistry, animal models, research in clinical specimens, and clinical studies, the group excels in true translational research.

Current projects include:
1) Hemostatic abnormalities in patients with liver disease
2) Extrahemostatic functions of platelets in damage and repair of the liver
3) Biochemistry of hemostasis

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http://www.rug.nl/staff/j.a.lisman/index