Category Archives: Psychiatry Res

Measuring BDNF in saliva using commercial ELISA: Results from a small pilot study.

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Measuring BDNF in saliva using commercial ELISA: Results from a small pilot study.
Psychiatry Res. 2017 Apr 22;254:340-346
Authors: Vrijen C, Schenk HM, Hartman CA, Oldehinkel AJ
Abstract
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Structural brain network analysis in families multiply affected with bipolar I disorder.

Structural brain network analysis in families multiply affected with bipolar I disorder.
Psychiatry Res. 2015 Aug 20;
Authors: Forde NJ, O’Donoghue S, Scanlon C, Emsell L, Chaddock C, Leemans A, Jeurissen B, Barker G… Continue reading

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Erythrocyte fatty acid profiles and plasma homocysteine, folate and vitamin B6 and B12 in recurrent depression: Implications for co-morbidity with cardiovascular disease.

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Erythrocyte fatty acid profiles and plasma homocysteine, folate and vitamin B6 and B12 in recurrent depression: Implications for co-morbidity with cardiovascular disease.

Psychiatry Res. 2015 Jun 27;

Authors: Assies J, Mocking RJ, Lok A, Koeter MW, Bockting CL, Visser I, Pouwer F, Ruhé HG, Schene AH

Abstract
Oxidative stress induced interactions between fatty acid (FA) and one-carbon metabolism may be involved in co-occurrence of major depressive disorder (MDD) and cardiovascular disease (CVD), which have been scarcely studied together. In 137 recurrent MDD-patients vs. 73 age- and sex-matched healthy controls, we simultaneously measured key components of one-carbon metabolism in plasma (homocysteine, folate, vitamins B6 and B12), and of FA-metabolism in red blood cell membranes [main polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and arachidonic acid (AA) and structural FA-indices (chain length, unsaturation, peroxidation)]. Results show significant positive associations of folate with EPA, DHA, and the peroxidation index, which were similar in patients and controls. After correction for confounders, these associations were lost except for EPA. Associations between B-vitamins and FA-parameters were non-significant, but also similar in patients and controls. Homocysteine and DHA were significantly less negatively associated in patients than in controls. In conclusion, these data indicate similarities but also differences in associations between parameters of one-carbon and FA-metabolism in recurrent MDD patients vs. controls, which may reflect differences in handling of oxidative stress. Further research should test the consequences of these differences, particularly the premature development of CVD in MDD.

PMID: 26260568 [PubMed – as supplied by publisher]

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Neural correlates of visuospatial working memory in attention-deficit/hyperactivity disorder and healthy controls.

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Neural correlates of visuospatial working memory in attention-deficit/hyperactivity disorder and healthy controls.
Psychiatry Res. 2015 Jul 3;
Authors: van Ewijk H, Weeda WD, Heslenfeld DJ, Luman M, H… Continue reading

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Depressive and anxiety disorders: Associated with losing or gaining weight over 2 years?

Depressive and anxiety disorders: Associated with losing or gaining weight over 2 years?
Psychiatry Res. 2015 Mar 31;
Authors: de Wit LM, van Straten A, Lamers F, Cuijpers P, Penninx BW
Abstract
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Assessing traumatic experiences in screening for PTSD in substance use disorder patients: What is the gain in addition to PTSD symptoms?

Assessing traumatic experiences in screening for PTSD in substance use disorder patients: What is the gain in addition to PTSD symptoms?
Psychiatry Res. 2015 Jan 28;
Authors: Kok T, de Haan H, van der Meer M, Najavit… Continue reading

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Similar cortical but not subcortical gray matter abnormalities in women with posttraumatic stress disorder with versus without dissociative identity disorder.

Similar cortical but not subcortical gray matter abnormalities in women with posttraumatic stress disorder with versus without dissociative identity disorder.
Psychiatry Res. 2015 Jan 21;
Authors: Chalavi S, Vissia E… Continue reading

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Relevance of Five-Factor Model personality traits for obsessive-compulsive symptoms in patients with psychotic disorders and their un-affected siblings.

Relevance of Five-Factor Model personality traits for obsessive-compulsive symptoms in patients with psychotic disorders and their un-affected siblings.
Psychiatry Res. 2014 Dec 10;
Authors: Schirmbeck F, Boyette LL,… Continue reading

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Longitudinal measurement invariance of the Beck Scale for Suicide Ideation.

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Longitudinal measurement invariance of the Beck Scale for Suicide Ideation.
Psychiatry Res. 2014 Dec 23;
Authors: de Beurs DP, Fokkema M, de Groot MH, de Keijser J, Kerkhof AJ
Abstract
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Mood dependence of perceived criticism: A significant null finding.

Mood dependence of perceived criticism: A significant null finding.

Psychiatry Res. 2014 Sep 10;

Authors: Gerlsma C, de Ruiter NM, Kingma W

Abstract
Five decades of research have shown that the quality of one׳s interactions with significant others, as captured in the expressed emotion (EE) concept, affects the course of various psychiatric and medical complaints. The key EE-component, interpersonal criticism, is increasingly assessed with the single-item Perceived Criticism Measure (PCM). The measure is highly practical and has shown good concurrent and predictive validity. Because the PCM relies on respondents׳ memories, ratings may be subject to mood bias. In this study we examined to what extent PCM-ratings are mood dependent. College students (N=150) provided data on mood and PCM before and after the induction of either a positive or negative mood. Although the mood induction was highly successful, PCM-ratings remained stable and appeared unaffected by changes in mood. This finding contradicts the robust mood-congruency-effect finding that the valence of one’s mood enhances the recollection of similarly valenced memories. This apparent stability bolsters the PCM’s construct validity and makes it less likely that high PCM-ratings simply reflect the negatively biased perceptions of distressed individuals.

PMID: 25242433 [PubMed – as supplied by publisher]

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Occupancy of serotonin transporters in the amygdala by paroxetine in association with attenuation of left amygdala activation by negative faces in major depressive disorder.

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Occupancy of serotonin transporters in the amygdala by paroxetine in association with attenuation of left amygdala activation by negative faces in major depressive disorder.

Psychiatry Res. 2014 Feb 28;221(2):155-61

Authors: Ruhé HG, Koster M, Booij J, van Herk M, Veltman DJ, Schene AH

Abstract
Amygdala hyperactivation in major depressive disorder (MDD) might be attenuated by selective serotonin reuptake inhibitors (SSRIs), but the working mechanism remains unclear. We hypothesized that higher amygdala serotonin transporter (SERT) occupancy by paroxetine results in greater attenuation of amygdala activation by negative facial expressions in MDD patients. We treated fifteen MDD patients (22-55 years) with paroxetine 20-50mg/day. After 6 and 12 weeks, we quantified (1) clinical response (≥50% decrease in Hamilton Depression Rating Scale (HDRS), (2) SERT occupancy in both amygdala measured by repeated [123I]β-CIT single photon emission computed tomography (SPECT), and (3) amygdala activation when viewing fearful and angry (negative) faces with repeated functional MRI scans. Response rates were 4/15 and 9/15 at 6 and 12 weeks, respectively. Attenuation of left amygdala activation was associated with amygdala SERT occupancy (P=0.006) and response (P=0.015). This association may provide a rationale for decreased limbic activity seen during treatment of MDD. It might also explain the rapid decrease in negative attentional bias and amygdala activation caused by SSRIs.

PMID: 24406081 [PubMed – indexed for MEDLINE]

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How do you feel? Detection of recurrent Major Depressive Disorder using a single-item screening tool.

How do you feel? Detection of recurrent Major Depressive Disorder using a single-item screening tool.
Psychiatry Res. 2014 Jul 10;
Authors: van Rijsbergen GD, Burger H, Hollon SD, Elgersma HJ, Kok GD, Dekker J, de Jo… Continue reading

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Opposite brain emotion-regulation patterns in identity states of dissociative identity disorder: A PET study and neurobiological model.

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Opposite brain emotion-regulation patterns in identity states of dissociative identity disorder: A PET study and neurobiological model.
Psychiatry Res. 2014 Jun 4;
Authors: Reinders AA, Willemsen AT, … Continue reading

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Validation of a short adaptation of the Mood and Anxiety Symptoms Questionnaire (MASQ) in adolescents and young adults.

Validation of a short adaptation of the Mood and Anxiety Symptoms Questionnaire (MASQ) in adolescents and young adults.
Psychiatry Res. 2013 Dec 18;
Authors: Lin A, Yung AR, Wigman JT, Killackey E, Baksheev G, Wardenaar KJ
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Implicit and explicit self-associations in bipolar disorder: A comparison with healthy controls and unipolar depressive disorder.

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Implicit and explicit self-associations in bipolar disorder: A comparison with healthy controls and unipolar depressive disorder.

Psychiatry Res. 2013 Dec 8;

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Normal brain activation in schizophrenia patients during associative emotional learning.

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Normal brain activation in schizophrenia patients during associative emotional learning.

Psychiatry Res. 2013 Oct 19;

Authors: Swart M, Liemburg EJ,…

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Lower cortisol levels predict recurrence in remitted patients with recurrent depression: a 5.5 year prospective study.

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Lower cortisol levels predict recurrence in remitted patients with recurrent depression: a 5.5 year prospective study.

Psychiatry Res. 2012 Dec 30;200(2-3):281-7

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The validity of patient- and clinician-rated measures of needs and the therapeutic relationship in psychosis: A pooled analysis.

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The validity of patient- and clinician-rated measures of needs and the therapeutic relationship in psychosis: A pooled analysis.
Psychiatry Res. 2013 Feb 26;
Authors: Reininghaus U, McCabe R, Slade M, Burns T,… Continue reading

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Evaluating the CANSAS self-report (CANSAS-P) as a screening instrument for care needs in people with psychotic and affective disorders.

Evaluating the CANSAS self-report (CANSAS-P) as a screening instrument for care needs in people with psychotic and affective disorders.

Psychiatry Res. 2011 Aug 15;188(3):456-8

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