Category Archives: Br J Anaesth

Do intravascular hypo- and hypervolaemia result in changes in central blood volumes?

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Do intravascular hypo- and hypervolaemia result in changes in central blood volumes?

Br J Anaesth. 2015 Oct 29;

Authors: Vos JJ, Scheeren TW,…

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Reply from the authorsAre we ready for non-invasive blood pressure monitoring?-reply.

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Reply from the authorsAre we ready for non-invasive blood pressure monitoring?-reply.
Br J Anaesth. 2015 Jul;115(1):130-1
Authors: Kalmar AF, Vos JJ, Poterman M, Scheeren TW
PMID: 26089450 [Pu… Continue reading

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Reply: the lure of inductivism.

Reply: the lure of inductivism.
Br J Anaesth. 2015 May;114(5):849
Authors: Sleigh J, Sanders R, Absolom A
PMID: 25904612 [PubMed – in process]

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NAP5: the tip of the iceberg, or all we need to know?

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NAP5: the tip of the iceberg, or all we need to know?
Br J Anaesth. 2014 Oct;113(4):527-30
Authors: Absalom AR, Green D
PMID: 25236893 [PubMed – in process]

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Comparison of continuous non-invasive finger arterial pressure monitoring with conventional intermittent automated arm arterial pressure measurement in patients under general anaesthesia.

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Comparison of continuous non-invasive finger arterial pressure monitoring with conventional intermittent automated arm arterial pressure measurement in patients under…

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Sympathetic regulation of cerebral blood flow in humans: a review.

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Sympathetic regulation of cerebral blood flow in humans: a review.

Br J Anaesth. 2013 Sep;111(3):361-7

Authors: ter Laan M, van Dijk JM, Elting JW, Staal…

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Comparison of arterial pressure and plethysmographic waveform-based dynamic preload variables in assessing fluid responsiveness and dynamic arterial tone in patients undergoing major hepatic resection.

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Comparison of arterial pressure and plethysmographic waveform-based dynamic preload variables in assessing fluid responsiveness and dynamic arterial tone in patients undergoing major hepatic resection.

Br J Anaesth. 2013 Jun;110(6):940-6

Authors: Vos JJ, Kalmar AF, Struys MM, Wietasch JK, Hendriks HG, Scheeren TW

Abstract
BACKGROUND: Dynamic preload variables to predict fluid responsiveness are based either on the arterial pressure waveform (APW) or on the plethysmographic waveform (PW). We compared the ability of APW-based variations in stroke volume (SVV) and pulse pressure (PPV) and of PW-based plethysmographic variability index (PVI) to predict fluid responsiveness and to track fluid changes in patients undergoing major hepatic resection. Furthermore, we assessed whether the PPV/SVV ratio, as a measure of dynamic arterial elastance (Eadyn), could predict a reduction in norepinephrine requirement after fluid administration.
METHODS: Thirty patients received i.v. fluid (15 ml kg(-1) in 30 min) after hepatic resection and were considered responders when stroke volume index (SVI) increased ≥20% after fluid administration. SVV and SVI were measured by the FloTrac-Vigileo(®) device, and PVI was measured by the Masimo Radical 7 pulse co-oximeter(®).
RESULTS: The areas under a receiver operating characteristic curve for SVV, PPV, and PVI were 0.81, 0.77, and 0.78, respectively. In responders, all dynamic variables, except PVI, decreased after fluid administration. Eadyn predicted a reduced norepinephrine requirement (AUC = 0.81).
CONCLUSIONS: In patients undergoing major hepatic resection, both APW- and PW-based dynamic preload variables predict fluid responsiveness (preload) to a similar extent. Most variables (except PVI) also tracked fluid changes. Eadyn, as a measure of arterial elastance (afterload), might be helpful to distinguish the origin of hypotension.
CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT01060683.

PMID: 23348202 [PubMed – indexed for MEDLINE]

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Visual metaphors on anaesthesia monitors do not improve anaesthetists’ performance in the operating theatre.

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Visual metaphors on anaesthesia monitors do not improve anaesthetists’ performance in the operating theatre.

Br J Anaesth. 2013 May;110(5):816-22

Authors: …

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Accuracy of non-invasive measurement of haemoglobin concentration by pulse co-oximetry during steady-state and dynamic conditions in liver surgery.

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Accuracy of non-invasive measurement of haemoglobin concentration by pulse co-oximetry during steady-state and dynamic conditions in liver surgery.

Br J Anaesth….

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Cerebral haemodynamic physiology during steep Trendelenburg position and CO2 pneumoperitoneum.

Cerebral haemodynamic physiology during steep Trendelenburg position and CO2 pneumoperitoneum.
Br J Anaesth. 2012 Jan 17;
Authors: Kalmar AF, Dewaele F, Foubert L, Hendrickx JF, Heeremans EH, Struys MM, Absalom A
Abstr… Continue reading

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Postoperative renal dysfunction and preoperative left ventricular dysfunction predispose patients to increased long-term mortality after coronary artery bypass graft surgery.

Postoperative renal dysfunction and preoperative left ventricular dysfunction predispose patients to increased long-term mortality after coronary artery bypass graft surgery.
Br J Anaesth. 2009 Jun;102(6):749-55
Authors: Loef … Continue reading

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Lung isolation with a new Y-shaped endobronchial blocking device, the EZ-Blocker.

Lung isolation with a new Y-shaped endobronchial blocking device, the EZ-Blocker.
Br J Anaesth. 2010 Jan;104(1):119-20
Authors: Mungroop HE, Wai PT, Morei MN, Loef BG, Epema AH
PMID: 20007802 [PubMed – indexed for MEDL… Continue reading

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Intravenous lidocaine infusion reduces bispectral index-guided requirements of propofol only during surgical stimulation.

Intravenous lidocaine infusion reduces bispectral index-guided requirements of propofol only during surgical stimulation.
Br J Anaesth. 2010 Oct;105(4):471-9
Authors: Hans GA, Lauwick SM, Kaba A, Bonhomme V, Struys MM, Hans PC… Continue reading

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Influence of obesity on propofol pharmacokinetics: derivation of a pharmacokinetic model.

Influence of obesity on propofol pharmacokinetics: derivation of a pharmacokinetic model.
Br J Anaesth. 2010 Oct;105(4):448-56
Authors: Cortínez LI, Anderson BJ, Penna A, Olivares L, Muñoz HR, Holford NH, Struys MM, Sepulved… Continue reading

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Steep Trendelenburg position, intracranial pressure, and dexamethasone.

Steep Trendelenburg position, intracranial pressure, and dexamethasone.
Br J Anaesth. 2010 Oct;105(4):548-9
Authors: George A, Kalmar AF
PMID: 20837727 [PubMed – indexed for MEDLINE]

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Opioid-induced hyperalgesia: pain hurts?

Opioid-induced hyperalgesia: pain hurts?
Br J Anaesth. 2010 Nov;105(5):555-7
Authors: Konopka KH, van Wijhe M
PMID: 20952429 [PubMed – indexed for MEDLINE]

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Predicting cardiac output responses to passive leg raising by a PEEP-induced increase in central venous pressure, in cardiac surgery patients.

Predicting cardiac output responses to passive leg raising by a PEEP-induced increase in central venous pressure, in cardiac surgery patients.
Br J Anaesth. 2011 Aug;107(2):150-6
Authors: Geerts BF, Aarts LP, Groeneveld AB, Ja… Continue reading

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Optimizing intravenous drug administration by applying pharmacokinetic/pharmacodynamic concepts.

Optimizing intravenous drug administration by applying pharmacokinetic/pharmacodynamic concepts.
Br J Anaesth. 2011 Jul;107(1):38-47
Authors: Struys MM, Sahinovic M, Lichtenbelt BJ, Vereecke HE, Absalom AR
Abstract
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Pressure monitoring during neuroendoscopy: new insights.

Pressure monitoring during neuroendoscopy: new insights.
Br J Anaesth. 2011 Aug;107(2):218-24
Authors: Dewaele F, Kalmar AF, Van Canneyt K, Vereecke H, Absalom A, Caemaert J, Struys MM, Van Roost D
Abstract
BAC… Continue reading

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Performance evaluation of paediatric propofol pharmacokinetic models in healthy young children.

Performance evaluation of paediatric propofol pharmacokinetic models in healthy young children.
Br J Anaesth. 2011 Oct;107(4):593-600
Authors: Sepúlveda P, Cortínez LI, Sáez C, Penna A, Solari S, Guerra I, Absalom AR
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