Category Archives: Cancer

Cancer Survivorship and Palliative Care: Shared Progress, Challenges, and Opportunities.

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Cancer Survivorship and Palliative Care: Shared Progress, Challenges, and Opportunities.
Cancer. 2018 Sep 11;:
Authors: Geerse OP, Lakin JR, Berendsen AJ, Alfano CM, Nekhlyudov L
PMID: 30204… Continue reading

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Current variations in childhood cancer supportive care in the Netherlands.

Current variations in childhood cancer supportive care in the Netherlands.

Cancer. 2015 Nov 20;

Authors: Loeffen EA, Mulder RL, van de Wetering MD, Font-Gonzalez A,…

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Physical activity and survival of postmenopausal, hormone receptor-positive breast cancer patients: Results of the Tamoxifen Exemestane Adjuvant Multicenter Lifestyle study.

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Physical activity and survival of postmenopausal, hormone receptor-positive breast cancer patients: Results of the Tamoxifen Exemestane Adjuvant Multicenter Lifestyle study.

Cancer. 2014 May 19;

Authors: de Glas NA, Fontein DB, Bastiaannet E, Pijpe A, Craen AJ, Liefers GJ, Nortier HJ, de Haes HJ, van de Velde CJ, van Leeuwen FE

Abstract
BACKGROUND: Physical activity has been related to improved breast cancer outcomes. Especially in the older breast cancer population, physical activity may be important because old age is associated with comorbidities and decreased physical function. The purpose of this study was to investigate the relation between physical activity and overall survival, breast cancer-specific survival, and recurrence in several age groups of postmenopausal breast cancer patients.
METHODS: The Tamoxifen Exemestane Adjuvant Multinational Lifestyle study was a side study of the Tamoxifen Exemestane Adjuvant Multinational trial and prospectively investigated lifestyle habits of postmenopausal, hormone receptor-positive breast cancer patients. The relations between prediagnosis and postdiagnosis physical activity and overall survival, breast cancer-specific survival, and recurrence-free survival were assessed with Cox regression and competing risk regression models.
RESULTS: Among 521 patients, high levels of physical activity before and after the diagnosis were associated with better overall survival (the multivariate hazard ratios were 0.50 [95% confidence interval = 0.26-0.98] and 0.57 (95% confidence interval = 0.26-1.40] for patients who were very active before and after the diagnosis, respectively, in comparison with inactive patients). This was most evident in patients who were 65 years old or older. Physical activity was not significantly associated with breast cancer-specific survival or the relapse-free period.
CONCLUSIONS: Overall survival was better for patients who were active before and after the diagnosis. In contrast with previous studies, breast cancer survival and the risk of recurrence were not significantly associated with physical activity. These findings confirmed the need for more studies investigating the use of physical activity to supplement breast cancer treatment in older patients. Cancer 2014. © 2014 American Cancer Society.

PMID: 24840230 [PubMed – as supplied by publisher]

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