Category Archives: Best Pract Res Clin Gastroenterol

Surgical management and autologous intestinal reconstruction in short bowel syndrome.

Surgical management and autologous intestinal reconstruction in short bowel syndrome.
Best Pract Res Clin Gastroenterol. 2016 Apr;30(2):263-80
Authors: Hommel MJ, van Baren R, Haveman JW
Abstract
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Genetics of celiac disease.

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Genetics of celiac disease.

Best Pract Res Clin Gastroenterol. 2015 Jun;29(3):399-412

Authors: Ricaño-Ponce I, Wijmenga C, Gutierrez-Achury J

Abstract
New insights into the underlying molecular pathophysiology of celiac disease (CeD) over the last few years have been guided by major advances in the fields of genetics and genomics. The development and use of the Immunochip genotyping platform paved the way for the discovery of 39 non-HLA loci associated to CeD, and for follow-up functional genomics studies that pinpointed new disease genes, biological pathways and regulatory elements. By combining information from genetics with gene expression data, it has become clear that CeD is a disease with a dysregulated immune response, which can probably occur in a variety of immune cells. This type of information is crucial for our understanding of the disease and for providing leads for developing alternative therapies to the current gluten-free diet. In this review, we place these genetic findings in a wider context and suggest how they can assist the clinical care of CeD patients.

PMID: 26060105 [PubMed – as supplied by publisher]

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How will insights from genetics translate to clinical practice in inflammatory bowel disease?

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How will insights from genetics translate to clinical practice in inflammatory bowel disease?
Best Pract Res Clin Gastroenterol. 2014 Jun;28(3):387-97
Authors: Festen EA, Weersma RK
Abstract
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Small bowel endoscopy in familial adenomatous polyposis and Lynch syndrome.

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Small bowel endoscopy in familial adenomatous polyposis and Lynch syndrome.

Best Pract Res Clin Gastroenterol. 2012 Jun;26(3):359-68

Authors: Koornstra…

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