Baby’s met een hoog risico op cerebrale parese ‘groeien’ in hun houdingsproblemen

​Anke Boxum: Postural control and reaching throughout infancy: in cerebral palsy and in typical development In Nederland wordt bijna elke dag een …

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Georganiseerde activiteiten goed voor gezondheid en schoolprestaties van pubers

Petr Bad’ura: Healthy adolescence in the context of leisure time. The role of organized and unstructured leisure-time activities​ Onderzoek onder …

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Fysieke beweging en schermgebruik bij adolescenten gaan vaak samen

​Jaroslava Kopčákovká: Physical activity, screen-based activities and their potential determinants: Active living during adolescence. Adolescenten …

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Compactere broodstructuur beter in preventie van diabetes

​Coby Eelderink: Starchy foods in the prevention of type 2 diabetes mellitus. Effects of food structure and composition on starch digestibility and …

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Studiemateriaal herhalen voordat studenten het vergeten

Dario Cecilio Fernandes: Knowledge and skills acquisition in medical students: exploring aspects of the curriculum Hoe kunnen medische kennis en …

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Geen afname van motorische flexibiliteit tijdens gezond ouder worden

​Christian Greve: Preservation of motor flexibility in healthy aging: flexibility in joint coordination is unaffected by age and task constraints in …

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Dysfunctional attitudes or extreme response style as predictors of depressive relapse and recurrence after mobile cognitive therapy for recurrent depression.

Dysfunctional attitudes or extreme response style as predictors of depressive relapse and recurrence after mobile cognitive therapy for recurrent depression.

J Affect Disord. 2018 Sep 08;243:48-54

Authors: Brouwer ME, Williams AD, Forand NR, DeRubeis RJ, Bockting CLH

Abstract
BACKGROUND: According to previous research, dysfunctional attitudes and/or scoring extreme on the end-point anchors of questionnaires of dysfunctional thinking predict depressive relapse/recurrence. Evidence that these two methods represent a risk for depressive relapse/recurrence is however mixed, due to differential or poorly defined concepts. The current study aimed to test the two methods.
METHODS: Remitted recurrently depressed patients with low residual depressive symptoms (N = 264) were recruited as part of a randomized controlled trial of the effectiveness of mobile Cognitive Therapy for recurrent depression versus treatment as usual. In the current secondary analysis, Cox regression models were conducted to test dysfunctional attitudes and extreme responding variables (assessed on the Dysfunctional Attitudes Scale [DAS]) as predictors of depressive relapse/recurrence within two years after randomization.
RESULTS: Data from 255 participants were analyzed. Results showed that DAS total scores at baseline significantly predicted depressive relapse/recurrence (Hazard Ratio [HR] = 1.01, p = .042). An index that reflects endorsement of habitual relative to functional responses was a significant predictor of depressive relapse/recurrence (HR = 2.11, p = .029).
LIMITATIONS: The current study employed a single measure to identify extreme responses and dysfunctional attitudes. Secondly, various statistical analyses were performed without correcting for multiple testing, which in turn increased the likelihood to finding significant results.
CONCLUSIONS: Current study confirmed both methods: People who scored higher on the DAS or had relatively more habitual than functional responses on the extreme positive ends of the DAS had a decreased time to depressive relapse/recurrence.

PMID: 30223139 [PubMed – as supplied by publisher]

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Biomarkers voorspellen effectieve behandeling van hartfalen

​Jasper Tromp: Biomarkers and personalized medicine in heart failure Patiënten met hartfalen kunnen mogelijk beter behandeld worden als ze op basis …

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Ataxie-tests voor volwassenen ook goed toepasbaar bij kinderen

​Rick Brandsma: Reliability of diagnostic measures in early onset ataxia Vergelijkend onderzoek van kinderneuroloog Rick Brandsma laat zien dat de …

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Rol van CBX7 in regulatie bloedstamcellen

Johannes Jung: The role of human CBX proteins in human benign and malignant hematopoiesis.​ Het eiwit CBX7 speelt een regulerende rol bij het …

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Inducing dissociation and schizotypal experiences through “vision-deforming” glasses.

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Inducing dissociation and schizotypal experiences through “vision-deforming” glasses.

Conscious Cogn. 2018 Sep 10;65:209-215

Authors: Renard SBS, Huntjens RJCR, Pijnenborg GHMM

Abstract
Derealization, depersonalization and schizotypal experiences are described as separate concepts but they can be hard to distinguish. One way to show the uniqueness of these concepts is by showing a dissociation between these experiences. The aim of this study was to experimentally induce derealization without inducing depersonalization or schizotypal experiences. Healthy participants watched a neutral video in one of four conditions: (1) with stroboscopic light, (2) while wearing deforming glasses, (3) with stroboscopic light and while wearing “vision deforming glasses” or (4) without any manipulation. The results show that the “vision deforming” glasses induced derealization without inducing depersonalization but not without inducing schizotypal experiences. The stroboscopic light showed no significant effect, nor was there a significant interaction between the stroboscopic light and the deforming glasses. The results indicate that using “vision deforming” glasses as a manipulation method can show a single dissociation between derealization and depersonalization but cannot dissociate derealization from state schizotypy. This association between derealization and schizotypal experiences might be helpful in understanding the high comorbidity rate between dissociative disorders and schizophrenia spectrum disorders.

PMID: 30212754 [PubMed – as supplied by publisher]

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[Factors influencing the referral of nursing home patients to the hospital].

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[Factors influencing the referral of nursing home patients to the hospital].

Tijdschr Gerontol Geriatr. 2018 Sep 10;:

Authors: Huls M, Pouw MA, Nieuwenhuizen N, van Munster BC, de Rooij SE

Abstract
INTRODUCTION: Hospitalisation may cause negative effects on elderly patients. Therefore, it is important that referral and admission of older nursing home patients is well-considered. The aim of this study is to investigate the factors that affect the decision making process.
METHOD: Questionnaire survey among elderly care physicians and physicians following the elderly care physician training program.
RESULTS: Of the 1,540 surveys, 200 were returned (response rate of 13%). Over 60% of the respondents had referred a nursing home patient to the hospital in the previous month. A stay at a geriatric rehabilitation ward, suspicion of a fracture, a good quality of life, a patient’s or family’s wish for referral, no treatment restrictions, and follow-up appointments in the hospital were factors which made referral to the hospital more likely according to the respondents. Medical specialist consultation and the in hospital presence of a physician specialised in geriatric care were considered to be important. Referral was less likely if a patient was diagnosed with dementia, had a low quality of life or had treatment restrictions.
CONCLUSION: Both patient-related and non-patient-related factors influence hospital referral of nursing home patients. Further research is needed to determine whether these different factors contribute to the different outcomes of a hospital admission, to facilitate proper decision-making for elderly care physicians.

PMID: 30203244 [PubMed – as supplied by publisher]

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Cancer Survivorship and Palliative Care: Shared Progress, Challenges, and Opportunities.

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Cancer Survivorship and Palliative Care: Shared Progress, Challenges, and Opportunities.

Cancer. 2018 Sep 11;:

Authors: Geerse OP, Lakin JR, Berendsen AJ, Alfano CM, Nekhlyudov L

PMID: 30204237 [PubMed – as supplied by publisher]

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Mother’s knowledge on prevention of mother-to-child transmission of HIV, Ethiopia: A cross sectional study.

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Mother’s knowledge on prevention of mother-to-child transmission of HIV, Ethiopia: A cross sectional study.

PLoS One. 2018;13(9):e0203043

Authors: Alemu YM, Habtewold TD, Alemu SM

Abstract
OBJECTIVE: To identify proportion of and factors for comprehensive knowledge on prevention of mother-to-child transmission of HIV in pregnant women attending antenatal care in Northern Ethiopia.
METHODS: A total of 416 pregnant women were interviewed between October 2012 and May 2013. Logistic regression analysis was used to identify factors for comprehensive knowledge on prevention of mother-to-child transmission of HIV.
RESULTS: The proportion of pregnant women, who have comprehensive knowledge on prevention of mother-to-child transmission of HIV, was 52%. The odds of having comprehensive knowledge on prevention of mother-to-child transmission of HIV were higher among pregnant women who were younger (16 to 24 years old) (Adjusted Odds Ratio (AOR) = 2.95; 95%CI: 1.20, 7.26), urban residents (AOR = 2.45; 95%CI: 1.39, 4.32), attending secondary education and above (AOR = 4.43; 95%CI: 2.40, 8.20), employed (AOR = 4.99;95%CI: 2.45, 10.16), have five children or more (AOR = 9.34; 95%CI:3.78, 23.07), have favored attitude towards HIV positive living (AOR = 2.53; 95%CI: 1.43, 4.44) and have perceived susceptibility to HIV (AOR = 10.72; 95%CI: 3.90, 29.39).
CONCLUSION: The proportion of women who have comprehensive knowledge on prevention of mother-to-child transmission of HIV in this study setting was low. Measures which will escalate mother’s knowledge on prevention of mother-to-child transmission of HIV should be emphasized. Efforts to improve mother’s knowledge on prevention of mother-to-child transmission of HIV should target women who were older age (> = 35years), rural residents, unemployed, not attending formal education, primigravids, have no favored attitude towards HIV positive living and have not perceived susceptibility to HIV.

PMID: 30204752 [PubMed – in process]

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A case report of a young adult with progressive bloody diarrhea, protein losing enteropathy and extended polyposis coli.

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A case report of a young adult with progressive bloody diarrhea, protein losing enteropathy and extended polyposis coli.

Gastroenterology. 2018 Sep 08;:

Authors: Borgerink MMH, Weersma RK, Visschedijk MC

PMID: 30205102 [PubMed – as supplied by publisher]

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Onderzoek naar beste manier om voortand te vervangen

​​​Elise Zuiderveld: Onderzoek naar beste manier om voortand te vervangen Een implantaat is een goede optie om een niet te behouden voortand te …

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Behoefte aan informatie en ondersteunende zorg bij borstkankerpatiënten in Mexico

​Adriana Perez Fortis: Supportive care needs and psychological complaints among Mexican breast cancer patients Borstkankerpatiënten in Mexico hebben …

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Toegang tot jeugdhulp onderzocht: aanknopingspunten voor de transformatie van de jeugdhulp

​​​Marieke Nanninga: Toegang tot jeugdhulp onderzocht: aanknopingspunten voor de transformatie van de jeugdhulp Dit proefschrift gaat over de toegang …

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Meer inzicht in mechanismen die aneuploïdie-tolerantie mogelijk maken

Judith Simon: Identifying aneuploidy-tolerating genes ​Bij ongeveer 70% van alle tumoren hebben de kankercellen een afwijkend chromosoomaantal. Dat …

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Bloedhersenbarrière beter in beeld met nieuwe tracer voor PET-scan

​Heli Anneli Savolainen: PET imaging of P-glycoprotein at the blood-brain barrier with new 18F-tracers De nieuw ontwikkelde tracer met de naam …

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