Nieuwe strategie voor identificatie van longkanker tijdens longkankerscreening met CT-scan

​Joan Walter: New nodules at incidence low-dose CT lung cancer screening Wereldwijd sterven er zo’n 1,6 miljoen mensen per jaar aan longkanker. Bij …

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Which disease features run in essential tremor families? A systematic review.

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Which disease features run in essential tremor families? A systematic review.

Parkinsonism Relat Disord. 2019 Oct 19;69:71-78

Authors: van der Stouwe AMM, Everlo CSJ, Tijssen MAJ

Abstract
Essential tremor is a common and highly heritable movement disorder. It is largely unknown, however, to what extent family members share overlapping symptoms. Such knowledge would be useful, as it may lead to the definition of familial essential tremor phenotypes, which will aid the ongoing search for genotypes. Also, this information can be used by clinicians in patient counselling. Therefore, we conducted a systematic review to provide an overview of the evidence on which essential tremor features run in families, to assess the literature’s strengths and weaknesses, and to provide recommendations for future studies. PubMed was searched resulting in 460 titles: sixteen articles ultimately proved fit for inclusion. The results are represented in line with the Axis 1 classification of tremor as published in the latest Consensus Statement. In summary, we found varying levels of positive evidence for familial aggregation of age at onset, disease progression, alcohol responsiveness, parkinsonism and dystonia. Evidence on midline tremor was conflicting. The evidence on familial clustering was negative for cerebellar signs and action tremor asymmetry. Although the level of evidence is modest, it seems that some disease features are indeed familial, while other features are not. We discuss complicating factors, such as state-vs-trait dependency of characteristics, the place of familial dystonia, and the development of diagnostic criteria for essential tremor over time. In the future, comprehensive replication studies are needed, with the addition of several characteristics that have not been investigated so far, as the next step towards discovery of essential tremor phenotypes.

PMID: 31698217 [PubMed – as supplied by publisher]

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Complicaties en optimalisatie van behandeling met medicijnen voor inflammatoire darmziekten

​Dorien Buurman: Complications and optimalisation of Mesalazine and anti-TNF-alpha therapy in inflammatory bowel disease Inflammatoire darmziekten …

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Synergieën en eind-effector kinematica in bewegingen van de bovenste ledematen

​Inge Tuitert: Synergies and end-effector kinematics in upper limb movements Als je een motorische handeling herhaaldelijk uitvoert, is deze nooit …

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Verbetering van bacteriële eiwitproductieprocessen door gerichte analyse en eliminatie van knelpunten

Jolanda Neef: A tale of two cell factories. Heterologous protein secretion by Bacillus subtilis and Lactococcus lactis ​Bacteriën, zoals de …

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Verhoogde bloeddruk bij de moeder tijdens de zwangerschap: identificatie en behandeling

Thomas Pereira Bernardes: Hypertensive disorders of pregnancy. Occurrence, recurrence, and management ​Wereldwijd zijn er meer dan 200 miljoen …

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(University Medical Center Groni*[ad] OR University Medical Centre Groni*[ad] OR university Medical Centre of Groni*[ad] OR university Medical Center of Groni*[ad] OR University Medical Center, Groni*[ad] OR University Medical Centre, Groni*[ad] OR university of groni*[ad] OR groningen universit*[ad] OR UMC groni*[ad] OR medical center groni*[ad] OR medical centre groni*[ad] OR university hospital groni*[ad] OR university groni*[ad] OR Universitair Medisch Centrum Groni*[ad] OR Rijksuniversiteit Groni*[ad] OR academic hospital groni*[ad] OR academisch ziekenhuis groni*[ad] OR azg[ad] OR UMCG[ad] OR 9713 GZ[ad] OR 9713GZ[ad] OR 9713 AV[ad] OR 9713AV[ad] OR hanzeplein[ad] OR deusinglaan[ad] OR (beatrix*[ad] AND groni*[ad]) OR (rug[ad] AND groni*[ad])); +109 new citations

109 new pubmed citations were retrieved for your search.
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(University Medical Center Groni*[ad] OR University Medical Centre Groni*[ad] OR university Medical Centre of Groni*[ad] OR university Medical Center of Groni*[ad] OR University Medical Center, Groni*[ad] OR University Medical Centre, Groni*[ad] OR university of groni*[ad] OR groningen universit*[ad] OR UMC groni*[ad] OR medical center groni*[ad] OR medical centre groni*[ad] OR university hospital groni*[ad] OR university groni*[ad] OR Universitair Medisch Centrum Groni*[ad] OR Rijksuniversiteit Groni*[ad] OR academic hospital groni*[ad] OR academisch ziekenhuis groni*[ad] OR azg[ad] OR UMCG[ad] OR 9713 GZ[ad] OR 9713GZ[ad] OR 9713 AV[ad] OR 9713AV[ad] OR hanzeplein[ad] OR deusinglaan[ad] OR (beatrix*[ad] AND groni*[ad]) OR (rug[ad] AND groni*[ad]))

These pubmed results were generated on 2019/11/05

PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books.
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Analyse van nieuwe hulpmiddelen en operatieve technieken voor KNO-patiënten

​Bertram De Kleijn: Medical devices for airway patients: a clinical evaluation of new products and techniques Er zijn veel medische hulpmiddelen …

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Mechanisme van acute myeloïde leukemie (AML)-stamcellen verder ontrafeld

Katharina Mattes: Biology of acute myeloid leukemia stem cells: The role of CITED2 and mitochondrial activity​ Acute myeloïde leukemie (AML) is een …

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Curriculumveranderingen in de opleiding Geneeskunde: de complexiteit van het invoeren van verandering

​Floor Velthuis: Unraveling the complexities of enacting change in undergraduate medical curricula Bij Geneeskunde-opleidingen is het gebruikelijk …

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Kunnen positieve emoties de lichamelijke gezondheid verbeteren? Een onderzoek naar enkele claims uit de positieve psychologie

​Nick Brown: Can positive emotions improve physical health? An examination of some claims from positive psychology Er zijn twee belangrijke redenen …

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Effect van sociale stress op de hersenen

​Bruno Lima Giacobbo: Social stress: the good, the bad, and the neurotrophic factor. Understanding the brain through PET imaging and molecular …

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The puborectal continence reflex functions independently of the pudendal nerve

The puborectal continence reflex functions independently of the pudendal nerve

Jonker, J. E., van Meegdenburg, M. M., Trzpis, M. & Broens, P. M. A., Nov-2019, In : Colorectal Disease. 21, 11, 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Original language English
Number of pages 8
Journal Colorectal Disease
Volume 21
Issue number 11
Publication status Published – Nov-2019
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Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF)

Original language English
Journal European Journal of Medicinal Chemistry
Publication status Published – 1-Nov-2019
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Somatostatin receptor imaging by SPECT and PET in patients with chronic inflammatory disorders: a systematic review

Somatostatin receptor imaging by SPECT and PET in patients with chronic inflammatory disorders: a systematic review

Anzola, L. K., Glaudemans, A. W. J. M., Dierckx, R. A. J. O., Martinez, F. A., Moreno, S. & Signore, A., Nov-2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, 12, p. 2496-2513 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Original language English
Pages (from-to) 2496-2513
Number of pages 18
Journal European Journal of Nuclear Medicine and Molecular Imaging
Volume 46
Issue number 12
Publication status Published – Nov-2019
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Clinical translation of the assets of biomedical engineering – a retrospective analysis with looks to the future

Clinical translation of the assets of biomedical engineering – a retrospective analysis with looks to the future

Ren, Y., Fagette, P. H., Hall, C. L., Broers, H., Grainger, D. W., Van Der Mei, H. C. & Busscher, H. J., Nov-2019, In : Expert review of medical devices. 16, 11, p. 913-922 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Original language English
Pages (from-to) 913-922
Number of pages 10
Journal Expert review of medical devices
Volume 16
Issue number 11
Publication status Published – Nov-2019
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Gene network approach reveals co-expression patterns in nasal and bronchial epithelium

Gene network approach reveals co-expression patterns in nasal and bronchial epithelium

Imkamp, K., Bernal, V., Grzegorzcyk, M., Horvatovich, P., Vermeulen, C. J., Heijink, I. H., Guryev, V., Kerstjens, H. A. M., van den Berge, M. & Faiz, A., 1-Nov-2019, In : Scientific Reports. 9, 1, 13 p., 15835.

Research output: Contribution to journalArticleAcademicpeer-review

Original language English
Article number 15835
Number of pages 13
Journal Scientific Reports
Volume 9
Issue number 1
Publication status Published – 1-Nov-2019
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Measuring handrim wheelchair propulsion in the lab: a critical analysis of stationary ergometers

Measuring handrim wheelchair propulsion in the lab: a critical analysis of stationary ergometers

De Klerk, R., Vegter, R. J. K., Goosey-Tolfrey, V. L., Mason, B. S., Lenton, J. P., Veeger, H. E. J. & Van Der Woude, L. H. V., 31-Oct-2019, In : IEEE reviews in biomedical engineering. 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Original language English
Number of pages 17
Journal IEEE reviews in biomedical engineering
Early online date 2019
Publication status Published – 31-Oct-2019
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Associations of autozygosity with a broad range of human phenotypes

Associations of autozygosity with a broad range of human phenotypes

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T. M., Baumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J-F., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., de Haan, H. G., Harris, S. E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-Gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., van der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., van der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Aguilar-Salinas, C. A., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., de Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M-L., Chen, G., Chen, Y-D. I., Chen, Z., Chiu, Y-F., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Dörr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdóttir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M. O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. 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B., Wijmenga, C., Wong, T-Y., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 31-Oct-2019, In : Nature Communications. 10, 1, 17 p., 4957.

Research output: Contribution to journalArticleAcademicpeer-review

Original language English
Article number 4957
Number of pages 17
Journal Nature Communications
Volume 10
Issue number 1
Publication status Published – 31-Oct-2019
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IJzergebrek en hoge erytropoëtine spiegels: twee kanten van dezelfde medaille?

Michele Freerk Eisenga: Iron deficiency and erythropoietin excess: two sides of the same coin? Studies in patients with chronic kidney disease and in …

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